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A Single Active-Site Mutagenesis Confers Enhanced Activity and/or Changed Product Distribution to a Pentalenene Synthase from Streptomyces sp. PSKA01

Pentalenene is a ternary cyclic sesquiterpene formed via the ionization and cyclization of farnesyl pyrophosphate (FPP), which is catalyzed by pentalenene synthase (PentS). To better understand the cyclization reactions, it is necessary to identify more key sites and elucidate their roles in terms o...

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Detalles Bibliográficos
Autores principales: Liu, Hongshuang, Fang, Senbiao, Zhao, Lin, Men, Xiao, Zhang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045451/
https://www.ncbi.nlm.nih.gov/pubmed/36978783
http://dx.doi.org/10.3390/bioengineering10030392