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A Single Active-Site Mutagenesis Confers Enhanced Activity and/or Changed Product Distribution to a Pentalenene Synthase from Streptomyces sp. PSKA01
Pentalenene is a ternary cyclic sesquiterpene formed via the ionization and cyclization of farnesyl pyrophosphate (FPP), which is catalyzed by pentalenene synthase (PentS). To better understand the cyclization reactions, it is necessary to identify more key sites and elucidate their roles in terms o...
Autores principales: | Liu, Hongshuang, Fang, Senbiao, Zhao, Lin, Men, Xiao, Zhang, Haibo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045451/ https://www.ncbi.nlm.nih.gov/pubmed/36978783 http://dx.doi.org/10.3390/bioengineering10030392 |
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