Cargando…

IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer

(1) Background: Cancer stem cells (CSCs) are a small cell population associated with chemoresistance, metastasis and increased mortality rate in oral cancer. Interferon-induced proteins with tetratricopeptide repeats 2 (IFIT2) depletion results in epithelial to mesenchymal transition, invasion, meta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Kuo-Chu, Regmi, Prabha, Liu, Chung-Ji, Lo, Jeng-Fan, Lee, Te-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045464/ https://www.ncbi.nlm.nih.gov/pubmed/36979874 http://dx.doi.org/10.3390/biomedicines11030896

Ejemplares similares

SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells
por: Regmi, Prabha, et al.
Publicado: (2020)

IFIT2‐depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice
por: Lai, Kuo‐Chu, et al.
Publicado: (2022)

Emerging Functions of Human IFIT Proteins in Cancer
por: Pidugu, Vijaya Kumar, et al.
Publicado: (2019)

Lysyl oxidase‐like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3
por: Lu, Yi‐Jie, et al.
Publicado: (2023)

The roles and mechanism of IFIT5 in bladder cancer epithelial–mesenchymal transition and progression
por: Huang, Jun, et al.
Publicado: (2019)

IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA
por: Fleith, Renata C, et al.
Publicado: (2018)

Clinical significance of IFIT2 expression in human renal cancer tissues
por: Xu, Bin, et al.
Publicado: (2020)

Inhibition of Proteasome Activity Induces Aggregation of IFIT2 in the Centrosome and Enhances IFIT2-Induced Cell Apoptosis
por: Chen, Limin, et al.
Publicado: (2017)

SARS-CoV-2 Uses Nonstructural Protein 16 to Evade Restriction by IFIT1 and IFIT3
por: Schindewolf, Craig, et al.
Publicado: (2022)

SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3
por: Schindewolf, Craig, et al.
Publicado: (2023)

PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2
por: Shen, Hui, et al.
Publicado: (2018)

COL8A1 Promotes NSCLC Progression Through IFIT1/IFIT3-Mediated EGFR Activation
por: Zan, Xiangyi, et al.
Publicado: (2022)

How Different Pathologies Are Affected by IFIT Expression
por: Franco, Justin H., et al.
Publicado: (2023)

Overexpression of IFN-induced protein with tetratricopeptide repeats 3 (IFIT3) in pancreatic cancer: cellular “pseudoinflammation” contributing to an aggressive phenotype
por: Niess, Hanno, et al.
Publicado: (2014)

Baicalein Suppresses Stem Cell-Like Characteristics in Radio- and Chemoresistant MDA-MB-231 Human Breast Cancer Cells through Up-Regulation of IFIT2
por: Koh, So Yae, et al.
Publicado: (2019)

Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells
por: Mears, Harriet V., et al.
Publicado: (2019)

IFITs: Emerging Roles as Key Anti-Viral Proteins
por: Vladimer, Gregory I., et al.
Publicado: (2014)

The broad-spectrum antiviral functions of IFIT and IFITM proteins
por: Diamond, Michael S., et al.
Publicado: (2012)

Kinetic analysis of IFIT1 and IFIT5 interactions with different native and engineered RNAs and its consequences for designing mRNA-based therapeutics
por: Miedziak, Beata, et al.
Publicado: (2020)

LncRNA RP5-998N21.4 promotes immune defense through upregulation of IFIT2 and IFIT3 in schizophrenia
por: Guo, Bo, et al.
Publicado: (2022)

Mouse Ifit1b is a cap1-RNA–binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c
por: Mears, Harriet V., et al.
Publicado: (2020)

Novel Antrodia cinnamomea Extract Reduced Cancer Stem-Like Phenotype Changes and Resensitized KRAS-Mutant Colorectal Cancer via a MicroRNA-27a Pathway
por: Lin, Tsung-Jen, et al.
Publicado: (2019)

Kruppel-like factor 13 acts as a tumor suppressor in thyroid carcinoma by downregulating IFIT1
por: Liu, Yang, et al.
Publicado: (2023)

Identification and Validation of Ifit1 as an Important Innate Immune Bottleneck
por: McDermott, Jason E., et al.
Publicado: (2012)

Interferon Induced IFIT Family Genes in Host Antiviral Defense
por: Zhou, Xiang, et al.
Publicado: (2013)

I19 Antiviral actions of the interferon-inducible IFIT proteins
por: Sen, G.
Publicado: (2012)

Molecular identification and transcriptional regulation of porcine IFIT2 gene
por: Yang, Xiuqin, et al.
Publicado: (2018)

Serum depletion induced cancer stem cell-like phenotype due to nitric oxide synthesis in oncogenic HRas transformed cells
por: Monji, Keisuke, et al.
Publicado: (2016)

Increased Interferon-Induced Protein With Tetracopeptides (IFITs) Reduces Mycobacterial Growth
por: Madhvi, Abhilasha, et al.
Publicado: (2022)

Cancer stem cells and early stage basal-like breast cancer
por: Lo, Pang-Kuo, et al.
Publicado: (2016)

Bioinformation Analysis Reveals IFIT1 as Potential Biomarkers in Central Nervous System Tuberculosis
por: Qiao, Wenbin, et al.
Publicado: (2022)

IFIT3 and IFIT5 Play Potential Roles in Innate Immune Response of Porcine Pulmonary Microvascular Endothelial Cells to Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus
por: Wu, Yanmei, et al.
Publicado: (2022)

The diagnostic/prognostic roles and biological function of the IFIT family members in acute myeloid leukemia
por: Zhao, YiFan, et al.
Publicado: (2023)

Inflammatory IFIT3 renders chemotherapy resistance by regulating post-translational modification of VDAC2 in pancreatic cancer
por: Wang, Zhefang, et al.
Publicado: (2020)

Stem cell-like T cell depletion in the recurrent head and neck cancer immune microenvironment
por: Chen, Linda, et al.
Publicado: (2023)

The Matrisome Is Associated with Metabolic Reprograming in Stem-like Phenotypes of Gastric Cancer
por: Sung, Ji-Yong, et al.
Publicado: (2022)

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA
por: Habjan, Matthias, et al.
Publicado: (2013)

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins
por: Abbas, Yazan M., et al.
Publicado: (2013)

IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells
por: Chico, Veronica, et al.
Publicado: (2019)

Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection
por: Kimura, Taishi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_e741thqt5bruocom45facnd7jj