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A transcriptomic pan-cancer signature for survival prognostication and prediction of immunotherapy response based on endothelial senescence
BACKGROUND: The microvascular endothelium inherently controls nutrient delivery, oxygen supply, and immune surveillance of malignant tumors, thus representing both biological prerequisite and therapeutic vulnerability in cancer. Recently, cellular senescence emerged as a fundamental characteristic o...
Autores principales: | Wu, Zhengquan, Uhl, Bernd, Gires, Olivier, Reichel, Christoph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045484/ https://www.ncbi.nlm.nih.gov/pubmed/36978029 http://dx.doi.org/10.1186/s12929-023-00915-5 |
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