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Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases

The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on...

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Autores principales: Li Pomi, Federica, Papa, Vincenzo, Borgia, Francesco, Vaccaro, Mario, Allegra, Alessandro, Cicero, Nicola, Gangemi, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045493/
https://www.ncbi.nlm.nih.gov/pubmed/36978928
http://dx.doi.org/10.3390/antiox12030680
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author Li Pomi, Federica
Papa, Vincenzo
Borgia, Francesco
Vaccaro, Mario
Allegra, Alessandro
Cicero, Nicola
Gangemi, Sebastiano
author_facet Li Pomi, Federica
Papa, Vincenzo
Borgia, Francesco
Vaccaro, Mario
Allegra, Alessandro
Cicero, Nicola
Gangemi, Sebastiano
author_sort Li Pomi, Federica
collection PubMed
description The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on the skin, with a focus on the newly emerging molecular mechanisms involved, providing extensive scientific evidence of its anti-inflammatory, antimicrobial, wound-healing and anticancer activity in dermatological practice. The search was conducted on articles concerning in vitro and in vivo studies in both animals and humans. The results obtained confirm the antioxidant role of R. officinalis. This assumption derives the possibility of using R. officinalis or its bioactive elements for the treatment of inflammatory and infectious skin pathologies. However, although the use of rosemary in the treatment of skin diseases represents a fascinating line of research, future perspectives still require large and controlled clinical trials in order to definitively elucidate the real impact of this plant and its components in clinical practice.
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spelling pubmed-100454932023-03-29 Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases Li Pomi, Federica Papa, Vincenzo Borgia, Francesco Vaccaro, Mario Allegra, Alessandro Cicero, Nicola Gangemi, Sebastiano Antioxidants (Basel) Review The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on the skin, with a focus on the newly emerging molecular mechanisms involved, providing extensive scientific evidence of its anti-inflammatory, antimicrobial, wound-healing and anticancer activity in dermatological practice. The search was conducted on articles concerning in vitro and in vivo studies in both animals and humans. The results obtained confirm the antioxidant role of R. officinalis. This assumption derives the possibility of using R. officinalis or its bioactive elements for the treatment of inflammatory and infectious skin pathologies. However, although the use of rosemary in the treatment of skin diseases represents a fascinating line of research, future perspectives still require large and controlled clinical trials in order to definitively elucidate the real impact of this plant and its components in clinical practice. MDPI 2023-03-09 /pmc/articles/PMC10045493/ /pubmed/36978928 http://dx.doi.org/10.3390/antiox12030680 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Li Pomi, Federica
Papa, Vincenzo
Borgia, Francesco
Vaccaro, Mario
Allegra, Alessandro
Cicero, Nicola
Gangemi, Sebastiano
Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
title Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
title_full Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
title_fullStr Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
title_full_unstemmed Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
title_short Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
title_sort rosmarinus officinalis and skin: antioxidant activity and possible therapeutical role in cutaneous diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045493/
https://www.ncbi.nlm.nih.gov/pubmed/36978928
http://dx.doi.org/10.3390/antiox12030680
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