Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals

BACKGROUND: Both Alzheimer’s disease (AD) genetic risk factors and indices of cognitive reserve (CR) influence risk of cognitive decline, but it remains unclear whether they interact. This study examined whether a CR index score modifies the relationship between AD genetic risk factors and long-term...

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Detalles Bibliográficos
Autores principales: Pettigrew, Corinne, Nazarovs, Jurijs, Soldan, Anja, Singh, Vikas, Wang, Jiangxia, Hohman, Timothy, Dumitrescu, Logan, Libby, Julia, Kunkle, Brian, Gross, Alden L., Johnson, Sterling, Lu, Qiongshi, Engelman, Corinne, Masters, Colin L., Maruff, Paul, Laws, Simon M., Morris, John C., Hassenstab, Jason, Cruchaga, Carlos, Resnick, Susan M., Kitner-Triolo, Melissa H., An, Yang, Albert, Marilyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045505/
https://www.ncbi.nlm.nih.gov/pubmed/36978190
http://dx.doi.org/10.1186/s13195-023-01206-9

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