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Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants

Petroleum hydrocarbons are relatively recalcitrant compounds, and as contaminants, they are one of the most serious environmental problems. n-Alkanes are important constituents of petroleum hydrocarbons. Advances in synthetic biology and metabolic engineering strategies have made n-alkane biodegrada...

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Detalles Bibliográficos
Autores principales: Wang, Minzhen, Ding, Mingzhu, Yuan, Yingjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045523/
https://www.ncbi.nlm.nih.gov/pubmed/36978738
http://dx.doi.org/10.3390/bioengineering10030347
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author Wang, Minzhen
Ding, Mingzhu
Yuan, Yingjin
author_facet Wang, Minzhen
Ding, Mingzhu
Yuan, Yingjin
author_sort Wang, Minzhen
collection PubMed
description Petroleum hydrocarbons are relatively recalcitrant compounds, and as contaminants, they are one of the most serious environmental problems. n-Alkanes are important constituents of petroleum hydrocarbons. Advances in synthetic biology and metabolic engineering strategies have made n-alkane biodegradation more designable and maneuverable for solving environmental pollution problems. In the microbial degradation of n-alkanes, more and more degradation pathways, related genes, microbes, and alkane hydroxylases have been discovered, which provide a theoretical basis for the further construction of degrading strains and microbial communities. In this review, the current advances in the microbial degradation of n-alkanes under aerobic condition are summarized in four aspects, including the biodegradation pathways and related genes, alkane hydroxylases, engineered microbial chassis, and microbial community. Especially, the microbial communities of “Alkane-degrader and Alkane-degrader” and “Alkane-degrader and Helper” provide new ideas for the degradation of petroleum hydrocarbons. Surfactant producers and nitrogen providers as a “Helper” are discussed in depth. This review will be helpful to further achieve bioremediation of oil-polluted environments rapidly.
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spelling pubmed-100455232023-03-29 Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants Wang, Minzhen Ding, Mingzhu Yuan, Yingjin Bioengineering (Basel) Review Petroleum hydrocarbons are relatively recalcitrant compounds, and as contaminants, they are one of the most serious environmental problems. n-Alkanes are important constituents of petroleum hydrocarbons. Advances in synthetic biology and metabolic engineering strategies have made n-alkane biodegradation more designable and maneuverable for solving environmental pollution problems. In the microbial degradation of n-alkanes, more and more degradation pathways, related genes, microbes, and alkane hydroxylases have been discovered, which provide a theoretical basis for the further construction of degrading strains and microbial communities. In this review, the current advances in the microbial degradation of n-alkanes under aerobic condition are summarized in four aspects, including the biodegradation pathways and related genes, alkane hydroxylases, engineered microbial chassis, and microbial community. Especially, the microbial communities of “Alkane-degrader and Alkane-degrader” and “Alkane-degrader and Helper” provide new ideas for the degradation of petroleum hydrocarbons. Surfactant producers and nitrogen providers as a “Helper” are discussed in depth. This review will be helpful to further achieve bioremediation of oil-polluted environments rapidly. MDPI 2023-03-10 /pmc/articles/PMC10045523/ /pubmed/36978738 http://dx.doi.org/10.3390/bioengineering10030347 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wang, Minzhen
Ding, Mingzhu
Yuan, Yingjin
Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants
title Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants
title_full Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants
title_fullStr Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants
title_full_unstemmed Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants
title_short Bioengineering for the Microbial Degradation of Petroleum Hydrocarbon Contaminants
title_sort bioengineering for the microbial degradation of petroleum hydrocarbon contaminants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045523/
https://www.ncbi.nlm.nih.gov/pubmed/36978738
http://dx.doi.org/10.3390/bioengineering10030347
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