Cargando…

Carnosic Acid Ameliorates Indomethacin-Induced Gastric Ulceration in Rats by Alleviating Oxidative Stress and Inflammation

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and indomethacin (IND) are the most commonly prescribed for inflammation or pain. However, widespread use causes several adverse effects, such as gastric ulcers, upper gastric system bleeding, and erosions. Carnosic acid (CA) is an import...

Descripción completa

Detalles Bibliográficos
Autores principales:	Danisman, Betul, Cicek, Betul, Yildirim, Serkan, Bolat, Ismail, Kantar, Deniz, Golokhvast, Kirill S., Nikitovic, Dragana, Tsatsakis, Aristidis, Taghizadehghalehjoughi, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045571/ https://www.ncbi.nlm.nih.gov/pubmed/36979808 http://dx.doi.org/10.3390/biomedicines11030829

Ejemplares similares

Flavonoid-Rich Sambucus nigra Berry Extract Enhances Nrf2/HO-1 Signaling Pathway Activation and Exerts Antiulcerative Effects In Vivo
por: Cicek, Betul, et al.
Publicado: (2023)

Chlorogenic Acid Attenuates Doxorubicin-Induced Oxidative Stress and Markers of Apoptosis in Cardiomyocytes via Nrf2/HO-1 and Dityrosine Signaling
por: Cicek, Betul, et al.
Publicado: (2023)

Artichoke (Cynara Scolymus) Methanolic Leaf Extract Alleviates Diethylnitrosamine-Induced Toxicity in BALB/c Mouse Brain: Involvement of Oxidative Stress and Apoptotically Related Klotho/PPARγ Signaling
por: Cicek, Betul, et al.
Publicado: (2022)

Sorafenib Alleviates Inflammatory Signaling of Tumor Microenvironment in Precancerous Lung Injuries
por: Cicek, Betul, et al.
Publicado: (2023)

Fe(3)O(4) Nanoparticles in Combination with 5-FU Exert Antitumor Effects Superior to Those of the Active Drug in a Colon Cancer Cell Model
por: Genc, Sidika, et al.
Publicado: (2023)

Mechanistic understanding of nanoparticles’ interactions with extracellular matrix: the cell and immune system
por: Engin, Ayse Basak, et al.
Publicado: (2017)

Potential Neurotoxic Effects of Glioblastoma-Derived Exosomes in Primary Cultures of Cerebellar Neurons via Oxidant Stress and Glutathione Depletion
por: Genc, Sidika, et al.
Publicado: (2022)

The Effect of Metformin on Ethanol- and Indomethacin-Induced Gastric Ulcers in Rats
por: İpek, Betül Esra, et al.
Publicado: (2022)

Effect of the combination of Lactobacillus acidophilus (probiotic) with vitamin K3 and vitamin E on Escherichia coli and Staphylococcus aureus: An in vitro pathogen model
por: Celebi, Ozgur, et al.
Publicado: (2023)

[Corrigendum] Effect of the combination of Lactobacillus acidophilus (probiotic) with vitamin K3 and vitamin E on Escherichia coli and Staphylococcus aureus: An in vitro pathogen model and metastasis in vivo
por: Celebi, Ozgur, et al.
Publicado: (2023)

Proteoglycans and Immunobiology of Cancer—Therapeutic Implications
por: Tzanakakis, George, et al.
Publicado: (2019)

A mixture of 13 pesticides, contaminants, and food additives below individual NOAELs produces histopathological and organ weight changes in rats
por: Dinca, Viorica, et al.
Publicado: (2023)

Amphiphilic Poly-N-vinylpyrrolidone Nanoparticles as Carriers for Nonsteroidal, Anti-Inflammatory Drugs: Pharmacokinetic, Anti-Inflammatory, and Ulcerogenic Activity Study
por: Kuskov, Andrey, et al.
Publicado: (2022)

Cancer Microenvironment and Inflammation: Role of Hyaluronan
por: Nikitovic, Dragana, et al.
Publicado: (2015)

Lumican in Carcinogenesis—Revisited
por: Giatagana, Eirini-Maria, et al.
Publicado: (2021)

Deteriorated Vascular Homeostasis in Hypertension: Experimental Evidence from Aorta, Brain, and Pancreatic Vasculature
por: Taghizadeh, Hadi, et al.
Publicado: (2022)

Proteoglycans—Biomarkers and Targets in Cancer Therapy
por: Nikitovic, Dragana, et al.
Publicado: (2018)

Limonin ameliorates indomethacin‐induced intestinal damage and ulcers through Nrf2/ARE pathway
por: Jia, Bo, et al.
Publicado: (2023)

Proteoglycans in the Pathogenesis of Hormone-Dependent Cancers: Mediators and Effectors
por: Tzanakakis, George, et al.
Publicado: (2020)

Reproductive Effects of S. boulardii on Sub-Chronic Acetamiprid and Imidacloprid Toxicity in Male Rats
por: Sevim, Çiğdem, et al.
Publicado: (2023)

A Selective Histamine H4 Receptor Antagonist, JNJ7777120, Role on glutamate Transporter Activity in Chronic Depression
por: Yeni, Yesim, et al.
Publicado: (2022)

Effects of boric acid and potassium metaborate on cytokine levels and redox stress parameters in a wound model infected with methicillin-resistant Staphylococcus aureus
por: Celebi, Demet, et al.
Publicado: (2022)

Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies
por: Varmazyari, Atefeh, et al.
Publicado: (2020)

The Effect of Tobacco Smoke N-Nitrosamines, NNK and NDEA, and Nicotine, on DNA Mismatch Repair Mechanism and miRNA Markers, in Hypopharyngeal Squamous Cell Carcinoma: An In Vivo Model and Clinical Evidence
por: Doukas, Sotirios G., et al.
Publicado: (2022)

Tetramethylpyrazine ameliorates indomethacin-induced gastric ulcer in rats: Impact on oxidative, inflammatory, and angiogenic machineries
por: AlKreathy, Huda M., et al.
Publicado: (2020)

Ameliorative effects of ribes rubrum oil against gastric ulcers caused by indomethacin in experimental models
por: Elsadek, Mohamed Farouk, et al.
Publicado: (2022)

Biglycan Regulates MG63 Osteosarcoma Cell Growth Through a LPR6/β-Catenin/IGFR-IR Signaling Axis
por: Aggelidakis, John, et al.
Publicado: (2018)

Glycosaminoglycans: Carriers and Targets for Tailored Anti-Cancer Therapy
por: Berdiaki, Aikaterini, et al.
Publicado: (2021)

Quinoa (Chenopodium quinoa Willd.) supplemented cafeteria diet ameliorates glucose intolerance in rats
por: Ozcaliskan Ilkay, Hatice, et al.
Publicado: (2023)

Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast
por: Scheler, Ulschan, et al.
Publicado: (2016)

Matrix Effectors in the Pathogenesis of Keratinocyte-Derived Carcinomas
por: Kavasi, Rafaela-Maria, et al.
Publicado: (2022)

Cornu aspersum mucin attenuates indomethacins-induced gastric ulcers in mice via alleviating oxidative stress and inflammation
por: Salem, Maha B., et al.
Publicado: (2023)

Developing BIOTEL: A Semi-Automated Spreadsheet for Estimating Telomere Length and Biological Age
por: Tsatsakis, Aristidis, et al.
Publicado: (2019)

Lumican mediates HTB94 chondrosarcoma cell growth via an IGF-IR/Erk1/2 axis
por: Papoutsidakis, Antonis, et al.
Publicado: (2020)

Obesity - a risk factor for increased COVID-19 prevalence, severity and lethality
por: Petrakis, Demetrios, et al.
Publicado: (2020)

The Role of IGF/IGF-IR-Signaling and Extracellular Matrix Effectors in Bone Sarcoma Pathogenesis
por: Tzanakakis, George N., et al.
Publicado: (2021)

Effect of felodipine on indomethacin-induced gastric ulcers in rats
por: Akbaş, Nergis, et al.
Publicado: (2023)

Protein bio-corona: critical issue in immune nanotoxicology
por: Neagu, Monica, et al.
Publicado: (2016)

1-Deoxynojirimycin (DNJ) Ameliorates Indomethacin-Induced Gastric Ulcer in Mice by Affecting NF-kappaB Signaling Pathway
por: Piao, Xuehua, et al.
Publicado: (2018)

8-Hydroxydeoxyguanosine as a biomarker of oxidative DNA damage in workers exposed to low-dose benzene
por: Fenga, Concettina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5nqkfa6574v2brncltfr1af4od