Designing Effective Multi-Target Drugs and Identifying Biomarkers in Recurrent Pregnancy Loss (RPL) Using In Vivo, In Vitro, and In Silico Approaches

Recurrent pregnancy loss (RPL) occurs in approximately 5% of women. Despite an abundance of evidence, the molecular mechanism of RPL’s pathology remains unclear. Here, we report the protective role of polo-like kinase 1 (PLK1) during RPL. We aimed to construct an RPL network utilizing GEO datasets a...

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Detalles Bibliográficos
Autores principales: Ramírez-Coronel, Andrés Alexis, Rostami, Amirabbas, Younus, Laith A., Arias Gonzáles, José Luis, Lafta, Methaq Hadi, Amin, Ali H., Saadoon, Mohammed Abdulkadhim, Salman, Hayder Mahmood, Bahrami, Abolfazl, Feilei, Rossa, Akhavan-Sigari, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045586/
https://www.ncbi.nlm.nih.gov/pubmed/36979858
http://dx.doi.org/10.3390/biomedicines11030879

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