Rescue of Dopamine Neurons from Iron-Dependent Ferroptosis by Doxycycline and Demeclocycline and Their Non-Antibiotic Derivatives

Several studies have reported that the tetracycline (TC) class antibiotic doxycycline (DOX) is effective against Parkinson’s disease (PD) pathomechanisms. The aim of the present work was three-fold: (i) Establish a model system to better characterize neuroprotection by DOX; (ii) Compare the rescue e...

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Detalles Bibliográficos
Autores principales: Tourville, Aurore, Viguier, Sarah, González-Lizárraga, Florencia, Tomas-Grau, Rodrigo Hernán, Ramirez, Paola, Brunel, Jean-Michel, Dos Santos Pereira, Mauricio, Del-Bel, Elaine, Chehin, Rosana, Ferrié, Laurent, Raisman-Vozari, Rita, Figadère, Bruno, Michel, Patrick Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045597/
https://www.ncbi.nlm.nih.gov/pubmed/36978822
http://dx.doi.org/10.3390/antiox12030575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045597/
https://www.ncbi.nlm.nih.gov/pubmed/36978822
http://dx.doi.org/10.3390/antiox12030575

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