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Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey

BACKGROUND: An investigation of trends of incidence and net survival (NS) for endometrial cancer in Sweden. METHODS: Morphologically verified endometrial carcinoma diagnosed 1960 to 2014 were collected from the nation-wide Swedish Cancer Registry. Endometrial cancer patients were assessed with regar...

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Autores principales: Herbst, Filip, Dickman, Paul W., Moberg, Louise, Högberg, Thomas, Borgfeldt, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045609/
https://www.ncbi.nlm.nih.gov/pubmed/36973669
http://dx.doi.org/10.1186/s12885-023-10746-0
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author Herbst, Filip
Dickman, Paul W.
Moberg, Louise
Högberg, Thomas
Borgfeldt, Christer
author_facet Herbst, Filip
Dickman, Paul W.
Moberg, Louise
Högberg, Thomas
Borgfeldt, Christer
author_sort Herbst, Filip
collection PubMed
description BACKGROUND: An investigation of trends of incidence and net survival (NS) for endometrial cancer in Sweden. METHODS: Morphologically verified endometrial carcinoma diagnosed 1960 to 2014 were collected from the nation-wide Swedish Cancer Registry. Endometrial cancer patients were assessed with regards to time trends for incidence and 54,825 cases remained for survival analyses. Cases diagnosed 1995 to 2014 were categorized according to detailed morphology and from 2005 to 2014 FIGO stage was also categorized. RESULTS: There was a trend of increasing incidence of endometrial carcinoma for women above 55 years of age. NS was improved at 5- and 10-year follow-up. The 5-year net survival in 2010–2014 was 86%. The most prominent improvement in NS was found in the elderly women above 75 years of age. CONCLUSIONS: This study observed increased incidence of endometrial cancer in Sweden from 1960 to 2014. The progress in diagnostics and treatment, seem to have improved the net survival, especially in elderly women.
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spelling pubmed-100456092023-03-29 Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey Herbst, Filip Dickman, Paul W. Moberg, Louise Högberg, Thomas Borgfeldt, Christer BMC Cancer Research BACKGROUND: An investigation of trends of incidence and net survival (NS) for endometrial cancer in Sweden. METHODS: Morphologically verified endometrial carcinoma diagnosed 1960 to 2014 were collected from the nation-wide Swedish Cancer Registry. Endometrial cancer patients were assessed with regards to time trends for incidence and 54,825 cases remained for survival analyses. Cases diagnosed 1995 to 2014 were categorized according to detailed morphology and from 2005 to 2014 FIGO stage was also categorized. RESULTS: There was a trend of increasing incidence of endometrial carcinoma for women above 55 years of age. NS was improved at 5- and 10-year follow-up. The 5-year net survival in 2010–2014 was 86%. The most prominent improvement in NS was found in the elderly women above 75 years of age. CONCLUSIONS: This study observed increased incidence of endometrial cancer in Sweden from 1960 to 2014. The progress in diagnostics and treatment, seem to have improved the net survival, especially in elderly women. BioMed Central 2023-03-27 /pmc/articles/PMC10045609/ /pubmed/36973669 http://dx.doi.org/10.1186/s12885-023-10746-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Herbst, Filip
Dickman, Paul W.
Moberg, Louise
Högberg, Thomas
Borgfeldt, Christer
Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey
title Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey
title_full Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey
title_fullStr Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey
title_full_unstemmed Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey
title_short Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey
title_sort increased incidence and improved survival in endometrial cancer in sweden 1960–2014: a population-based registry survey
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045609/
https://www.ncbi.nlm.nih.gov/pubmed/36973669
http://dx.doi.org/10.1186/s12885-023-10746-0
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