An Integrated In Vivo/In Vitro Protein Production Platform for Site-Specific Antibody Drug Conjugates

The XpressCF+(®) cell-free protein synthesis system is a robust platform for the production of non-natural amino acids containing antibodies, which enable the site-specific conjugation of homogeneous antibody drug conjugates (ADCs) via click chemistry. Here, we present a robust and scalable means of...

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Detalles Bibliográficos
Autores principales: Hanson, Jeffrey, Groff, Dan, Carlos, Abi, Usman, Hans, Fong, Kevin, Yu, Abigail, Armstrong, Stephanie, Dwyer, Allison, Masikat, Mary Rose, Yuan, Dawei, Tran, Cuong, Heibeck, Tyler, Zawada, James, Chen, Rishard, Hallam, Trevor, Yin, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045668/
https://www.ncbi.nlm.nih.gov/pubmed/36978695
http://dx.doi.org/10.3390/bioengineering10030304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045668/
https://www.ncbi.nlm.nih.gov/pubmed/36978695
http://dx.doi.org/10.3390/bioengineering10030304

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