Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA

We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tick...

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Detalles Bibliográficos
Autores principales: Farrington, Marjorie, Elenz, Jamie, Ginsberg, Matthew, Chiu, Charles Y., Miller, Steve, Pangonis, Scott F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045675/
https://www.ncbi.nlm.nih.gov/pubmed/36958034
http://dx.doi.org/10.3201/eid2904.221005
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author Farrington, Marjorie
Elenz, Jamie
Ginsberg, Matthew
Chiu, Charles Y.
Miller, Steve
Pangonis, Scott F.
author_facet Farrington, Marjorie
Elenz, Jamie
Ginsberg, Matthew
Chiu, Charles Y.
Miller, Steve
Pangonis, Scott F.
author_sort Farrington, Marjorie
collection PubMed
description We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management.
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spelling pubmed-100456752023-04-01 Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA Farrington, Marjorie Elenz, Jamie Ginsberg, Matthew Chiu, Charles Y. Miller, Steve Pangonis, Scott F. Emerg Infect Dis Research Letter We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management. Centers for Disease Control and Prevention 2023-04 /pmc/articles/PMC10045675/ /pubmed/36958034 http://dx.doi.org/10.3201/eid2904.221005 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Farrington, Marjorie
Elenz, Jamie
Ginsberg, Matthew
Chiu, Charles Y.
Miller, Steve
Pangonis, Scott F.
Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA
title Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA
title_full Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA
title_fullStr Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA
title_full_unstemmed Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA
title_short Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA
title_sort powassan virus infection detected by metagenomic next-generation sequencing, ohio, usa
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045675/
https://www.ncbi.nlm.nih.gov/pubmed/36958034
http://dx.doi.org/10.3201/eid2904.221005
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