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Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State

It is well known that driving while fatigued is dangerous and can lead to serious traffic accidents. However, there is a lack of studies on the mechanism of fatigue. This paper sought to infer changes in the cardiovascular system through hand and head skin temperature peripheral factors via an integ...

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Autores principales: Ding, Xiaoling, He, Ying, Chen, Youqiang, Wang, Yueping, Long, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045716/
https://www.ncbi.nlm.nih.gov/pubmed/36978759
http://dx.doi.org/10.3390/bioengineering10030368
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author Ding, Xiaoling
He, Ying
Chen, Youqiang
Wang, Yueping
Long, Lili
author_facet Ding, Xiaoling
He, Ying
Chen, Youqiang
Wang, Yueping
Long, Lili
author_sort Ding, Xiaoling
collection PubMed
description It is well known that driving while fatigued is dangerous and can lead to serious traffic accidents. However, there is a lack of studies on the mechanism of fatigue. This paper sought to infer changes in the cardiovascular system through hand and head skin temperature peripheral factors via an integrated lumped parameter model. A multi-layer inner structure with variable blood perfusion was used to construct a full-body thermal model. The cardiovascular system model provided blood perfusion using lumped parameters. The peripheral resistance and heart rate in the cardiovascular system model were adjusted to match the experimental temperatures of the head and hands obtained from induced fatigue experiments. The simulation results showed that the heart rate and blood pressure decreased, and the peripheral skin resistance of the hands and head increased after fatigue. A decrease in heart rate and an increase in peripheral resistance affect the magnitude of blood flow to the periphery of the body, leading to a decrease in skin temperature during fatigue. The present integrated model elucidates a key effect of human fatigue on the cardiovascular system, which is expected to help improve the accuracy of fatigue monitoring systems.
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spelling pubmed-100457162023-03-29 Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State Ding, Xiaoling He, Ying Chen, Youqiang Wang, Yueping Long, Lili Bioengineering (Basel) Article It is well known that driving while fatigued is dangerous and can lead to serious traffic accidents. However, there is a lack of studies on the mechanism of fatigue. This paper sought to infer changes in the cardiovascular system through hand and head skin temperature peripheral factors via an integrated lumped parameter model. A multi-layer inner structure with variable blood perfusion was used to construct a full-body thermal model. The cardiovascular system model provided blood perfusion using lumped parameters. The peripheral resistance and heart rate in the cardiovascular system model were adjusted to match the experimental temperatures of the head and hands obtained from induced fatigue experiments. The simulation results showed that the heart rate and blood pressure decreased, and the peripheral skin resistance of the hands and head increased after fatigue. A decrease in heart rate and an increase in peripheral resistance affect the magnitude of blood flow to the periphery of the body, leading to a decrease in skin temperature during fatigue. The present integrated model elucidates a key effect of human fatigue on the cardiovascular system, which is expected to help improve the accuracy of fatigue monitoring systems. MDPI 2023-03-17 /pmc/articles/PMC10045716/ /pubmed/36978759 http://dx.doi.org/10.3390/bioengineering10030368 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ding, Xiaoling
He, Ying
Chen, Youqiang
Wang, Yueping
Long, Lili
Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State
title Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State
title_full Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State
title_fullStr Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State
title_full_unstemmed Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State
title_short Integrated Thermofluid Lumped Parameter Model for Analyzing Hemodynamics in Human Fatigue State
title_sort integrated thermofluid lumped parameter model for analyzing hemodynamics in human fatigue state
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045716/
https://www.ncbi.nlm.nih.gov/pubmed/36978759
http://dx.doi.org/10.3390/bioengineering10030368
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