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Enhanced Levels of Peroxisome-Derived H(2)O(2) Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells

Peroxisomes are functionally specialized organelles that harbor multiple hydrogen peroxide (H(2)O(2))-producing and -degrading enzymes. Given that this oxidant functions as a major redox signaling agent, peroxisomes have the intrinsic ability to mediate and modulate H(2)O(2)-driven processes, includ...

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Detalles Bibliográficos
Autores principales: Li, Hongli, Lismont, Celien, Costa, Cláudio F., Hussein, Mohamed A. F., Baes, Myriam, Fransen, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045779/
https://www.ncbi.nlm.nih.gov/pubmed/36978861
http://dx.doi.org/10.3390/antiox12030613