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Updates in KMT2A Gene Rearrangement in Pediatric Acute Lymphoblastic Leukemia

The KMT2A (formerly MLL) encodes the histone lysine-specific N-methyltransferase 2A and is mapped on chromosome 11q23. KMT2A is a frequent target for recurrent translocations in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), or mixed lineage (biphenotypic) leukemia (MLL). Over 90...

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Detalles Bibliográficos
Autores principales:	Górecki, Mateusz, Kozioł, Ilona, Kopystecka, Agnieszka, Budzyńska, Julia, Zawitkowska, Joanna, Lejman, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045821/ https://www.ncbi.nlm.nih.gov/pubmed/36979800 http://dx.doi.org/10.3390/biomedicines11030821

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