Increased Renal Medullary NOX-4 in Female but Not Male Mice during the Early Phase of Type 1 Diabetes: Potential Role of ROS in Upregulation of TGF-β1 and Fibronectin in Collecting Duct Cells

Chronic diabetes mellitus (DM) can lead to kidney damage associated with increased reactive oxygen species (ROS), proteinuria, and tubular damage. Altered protein expression levels of transforming growth factor-beta 1 (TGF-β1), fibronectin, and renal NADPH oxidase (NOX-4) are associated with the pro...

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Detalles Bibliográficos
Autores principales: Casado-Barragán, Felipe, Lazcano-Páez, Geraldine, Larenas, Paulina E., Aguirre-Delgadillo, Monserrat, Olivares-Aravena, Fernanda, Witto-Oyarce, Daniela, Núñez-Allimant, Camila, Silva, Katherin, Nguyen, Quynh My, Cárdenas, Pilar, Kassan, Modar, Gonzalez, Alexis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045926/
https://www.ncbi.nlm.nih.gov/pubmed/36978977
http://dx.doi.org/10.3390/antiox12030729

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