Urinary ACE Phenotyping as a Research and Diagnostic Tool: Identification of Sex-Dependent ACE Immunoreactivity

Background: Angiotensin-converting enzyme (ACE) is highly expressed in renal proximal tubules, but ACE activity/levels in the urine are at least 100-fold lower than in the blood. Decreased proximal tubular ACE has been associated with renal tubular damage in both animal models and clinical studies....

Descripción completa

Detalles Bibliográficos
Autores principales: Kozuch, Alexander J., Petukhov, Pavel A., Fagyas, Miklos, Popova, Isolda A., Lindeblad, Matthew O., Bobkov, Alexander P., Kamalov, Armais A., Toth, Attila, Dudek, Steven M., Danilov, Sergei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045976/
https://www.ncbi.nlm.nih.gov/pubmed/36979933
http://dx.doi.org/10.3390/biomedicines11030953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045976/
https://www.ncbi.nlm.nih.gov/pubmed/36979933
http://dx.doi.org/10.3390/biomedicines11030953

Ejemplares similares