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Urinary ACE Phenotyping as a Research and Diagnostic Tool: Identification of Sex-Dependent ACE Immunoreactivity
Background: Angiotensin-converting enzyme (ACE) is highly expressed in renal proximal tubules, but ACE activity/levels in the urine are at least 100-fold lower than in the blood. Decreased proximal tubular ACE has been associated with renal tubular damage in both animal models and clinical studies....
Autores principales: | Kozuch, Alexander J., Petukhov, Pavel A., Fagyas, Miklos, Popova, Isolda A., Lindeblad, Matthew O., Bobkov, Alexander P., Kamalov, Armais A., Toth, Attila, Dudek, Steven M., Danilov, Sergei M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045976/ https://www.ncbi.nlm.nih.gov/pubmed/36979933 http://dx.doi.org/10.3390/biomedicines11030953 |
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