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Hepatotoxicity of Small Molecule Protein Kinase Inhibitors for Cancer

SIMPLE SUMMARY: This review reports the risk and management of the hepatotoxicity of all the approved protein kinase inhibitors (PKIs) for cancer. Hepatotoxicity is one of the major safety concerns of these drugs, as reflected by the discontinuation of the development of some of them due to liver in...

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Detalles Bibliográficos
Autores principales: Viganò, Mauro, La Milia, Marta, Grassini, Maria Vittoria, Pugliese, Nicola, De Giorgio, Massimo, Fagiuoli, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046041/
https://www.ncbi.nlm.nih.gov/pubmed/36980652
http://dx.doi.org/10.3390/cancers15061766