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CHEK2 Alterations in Pediatric Malignancy: A Single-Institution Experience

SIMPLE SUMMARY: Pediatric malignancies rarely occur, with 12,000–15,000 cases per year in the United States. Approximately 10% of pediatric cancers are thought to be secondary to germline alterations in cancer-predisposing genes based on numerous germline genomic analyses. CHEK2 germline loss-of-fun...

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Detalles Bibliográficos
Autores principales: Abdelghani, Eman, Schieffer, Kathleen M., Cottrell, Catherine E., Audino, Anthony, Zajo, Kristin, Shah, Nilay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046043/
https://www.ncbi.nlm.nih.gov/pubmed/36980535
http://dx.doi.org/10.3390/cancers15061649