Cargando…

Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice

As of October 2022, the COVID-19 pandemic continues to pose a major public health conundrum, with increased rates of symptomatic infections in vaccinated individuals. An ideal vaccine candidate for the prevention of outbreaks should be rapidly scalable, easy to administer, and able to elicit a poten...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarnelli, Giovanni, Del Re, Alessandro, Pesce, Marcella, Lu, Jie, Esposito, Giovanni, Sanseverino, Walter, Corpetti, Chiara, Basili Franzin, Silvia, Seguella, Luisa, Palenca, Irene, Rurgo, Sara, De Palma, Fatima Domenica Elisa, Zilli, Aurora, Esposito, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046078/ https://www.ncbi.nlm.nih.gov/pubmed/36979504 http://dx.doi.org/10.3390/biom13030569

Ejemplares similares

N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-α-Dependent Mechanism
por: Palenca, Irene, et al.
Publicado: (2022)

Next-Generation Probiotics for Inflammatory Bowel Disease
por: Pesce, Marcella, et al.
Publicado: (2022)

Cannabidiol inhibits SARS‐Cov‐2 spike (S) protein‐induced cytotoxicity and inflammation through a PPARγ‐dependent TLR4/NLRP3/Caspase‐1 signaling suppression in Caco‐2 cell line
por: Corpetti, Chiara, et al.
Publicado: (2021)

Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages
por: Del Re, Alessandro, et al.
Publicado: (2021)

Oral Adelmidrol Administration Up-Regulates Palmitoylethanolamide Production in Mice Colon and Duodenum through a PPAR-γ Independent Action
por: Del Re, Alessandro, et al.
Publicado: (2022)

Nutraceuticals and Diet Supplements in Crohn’s Disease: A General Overview of the Most Promising Approaches in the Clinic
por: De Conno, Barbara, et al.
Publicado: (2022)

Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice
por: Esposito, Giuseppe, et al.
Publicado: (2021)

The potential of cannabidiol in the COVID‐19 pandemic
por: Esposito, Giuseppe, et al.
Publicado: (2020)

A Palmitoylethanolamide Producing Lactobacillus paracasei Improves Clostridium difficile Toxin A-Induced Colitis
por: Esposito, Giuseppe, et al.
Publicado: (2021)

Can the enteric nervous system be an alternative entrance door in SARS-CoV2 neuroinvasion?
por: Esposito, Giuseppe, et al.
Publicado: (2020)

High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors
por: Seguella, Luisa, et al.
Publicado: (2021)

Sleeve Gastrectomy-Induced Body Mass Index Reduction Increases the Intensity of Taste Perception’s and Reduces Bitter-Induced Pleasantness in Severe Obesity
por: Rurgo, Sara, et al.
Publicado: (2022)

Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional Dyspepsia
por: Sarnelli, Giovanni, et al.
Publicado: (2020)

Probiotic Escherichia coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity
por: Ukena, Sya N., et al.
Publicado: (2007)

Leaky gut, dysbiosis, and enteric glia activation: the trilogy behind the intestinal origin of Parkinson’s disease
por: Seguella, Luisa, et al.
Publicado: (2019)

S100B Protein Stimulates Proliferation and Angiogenic Mediators Release through RAGE/pAkt/mTOR Pathway in Human Colon Adenocarcinoma Caco-2 Cells
por: Seguella, Luisa, et al.
Publicado: (2019)

Endocannabinoid‐related compounds in gastrointestinal diseases
por: Pesce, Marcella, et al.
Publicado: (2017)

Bioengineered Escherichia coli Nissle 1917 for tumour‐targeting therapy
por: Yu, Xiaoli, et al.
Publicado: (2019)

Gradient Magnetic Field Accelerates Division of E. coli Nissle 1917
por: Gorobets, Svitlana, et al.
Publicado: (2023)

Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917
por: Pérez-Berezo, Teresa, et al.
Publicado: (2017)

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917
por: Massip, Clémence, et al.
Publicado: (2019)

Escherichiacoli Nissle 1917 as a Novel Microrobot for Tumor-Targeted Imaging and Therapy
por: Liu, Qingyao, et al.
Publicado: (2021)

Pentamidine niosomes thwart S100B effects in human colon carcinoma biopsies favouring wtp53 rescue
por: Seguella, Luisa, et al.
Publicado: (2020)

Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activated Receptor Alpha (PPAR-α)-Dependent Manner
por: Sarnelli, Giovanni, et al.
Publicado: (2016)

Rifaximin Improves Clostridium difficile Toxin A-Induced Toxicity in Caco-2 Cells by the PXR-Dependent TLR4/MyD88/NF-κB Pathway
por: Esposito, Giuseppe, et al.
Publicado: (2016)

HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia
por: Sarnelli, Giovanni, et al.
Publicado: (2018)

E. coli Nissle 1917 Affects Salmonella Adhesion to Porcine Intestinal Epithelial Cells
por: Schierack, Peter, et al.
Publicado: (2011)

The Probiotic Escherichia coli Strain Nissle 1917 Combats Lambdoid Bacteriophages stx and λ
por: Bury, Susanne, et al.
Publicado: (2018)

The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice
por: Rodríguez-Nogales, Alba, et al.
Publicado: (2018)

Engineered E. coli Nissle 1917 for the reduction of vancomycin‐resistant Enterococcus in the intestinal tract
por: Geldart, Kathryn G., et al.
Publicado: (2018)

Effects of Escherichia coli strain Nissle 1917 on exercise-induced disruption of gastrointestinal integrity
por: Mooren, F. C., et al.
Publicado: (2020)

Transcriptional Profiling of the Probiotic Escherichia coli Nissle 1917 Strain under Simulated Microgravity
por: Yim, Jaewoo, et al.
Publicado: (2020)

Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut
por: Praveschotinunt, Pichet, et al.
Publicado: (2019)

No Genotoxicity Is Detectable for Escherichia coli Strain Nissle 1917 by Standard In Vitro and In Vivo Tests
por: Dubbert, Silke, et al.
Publicado: (2020)

Anti-inflammatory properties of Escherichia coli Nissle 1917 in a murine colitis model
por: Park, Jihye, et al.
Publicado: (2021)

Plasmid Vectors for in Vivo Selection-Free Use with the Probiotic E. coli Nissle 1917
por: Kan, Anton, et al.
Publicado: (2020)

Escherichia coli Nissle 1917 inhibits biofilm formation and mitigates virulence in Pseudomonas aeruginosa
por: Aljohani, Ahmad M., et al.
Publicado: (2023)

Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy
por: Tumas, Sarunas, et al.
Publicado: (2023)

Genotoxicity of Escherichia coli Nissle 1917 strain cannot be dissociated from its probiotic activity
por: Olier, Maïwenn, et al.
Publicado: (2012)

Functional investigation of the chromosomal ccdAB and hipAB operon in Escherichia coli Nissle 1917
por: Xu, Jun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f9cg7vhbqqi826kmgugu2pnbkg