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Pyruvate Dehydrogenase Kinase 4 Deficiency Increases Tumorigenesis in a Murine Model of Bladder Cancer

SIMPLE SUMMARY: Pyruvate dehydrogenase kinase 4 (PDK4) is a protein that serves as a switch for how the body regulates metabolism. Prior research indicates that blocking the effect of PDK4 with some drugs slows the growth of bladder cancer cells. These experiments relied on cancer cell lines and not...

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Detalles Bibliográficos
Autores principales:	Woolbright, Benjamin L., Rajendran, Ganeshkumar, Abbott, Erika, Martin, Austin, Didde, Ryan, Dennis, Katie, Harris, Robert A., Taylor, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046149/ https://www.ncbi.nlm.nih.gov/pubmed/36980540 http://dx.doi.org/10.3390/cancers15061654

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