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Current Understanding of Inherited Modifiers of FVIII Pharmacokinetic Variation
The inherited bleeding disorder hemophilia A involves the quantitative deficiency of the coagulation cofactor factor VIII (FVIII). Prophylactic treatment of severe hemophilia A patients with FVIII concentrates aims to reduce the frequency of spontaneous joint bleeding and requires personalized tailo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046206/ https://www.ncbi.nlm.nih.gov/pubmed/36998673 http://dx.doi.org/10.2147/PGPM.S383221 |