Cargando…

Machine Learning Model Based on Insulin Resistance Metagenes Underpins Genetic Basis of Type 2 Diabetes

Insulin resistance (IR) is considered the precursor and the key pathophysiological mechanism of type 2 diabetes (T2D) and metabolic syndrome (MetS). However, the pathways that IR shares with T2D are not clearly understood. Meta-analysis of multiple DNA microarray datasets could provide a robust set...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saxena, Aditya, Mathur, Nitish, Pathak, Pooja, Tiwari, Pradeep, Mathur, Sandeep Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046262/ https://www.ncbi.nlm.nih.gov/pubmed/36979367 http://dx.doi.org/10.3390/biom13030432

Ejemplares similares

Insulin Resistance Shows Stronger Correlation With Ectopic Liver Fat Instead of Visceral Fat in Asian Indians
por: Garg, Umesh Kumar, et al.
Publicado: (2021)

Whole transcriptome RNA-seq reveals key regulatory factors involved in type 2 diabetes pathology in peripheral fat of Asian Indians
por: Saxena, Aditya, et al.
Publicado: (2021)

Copy Number Variations Are More Frequent on Chromosome 14 as Compared to X Chromosome in Suspected Turner Syndrome Girls - A Chromosomal Microarray Analysis
por: Purwar, Naincy, et al.
Publicado: (2021)

Diabetes and Insulin Resistance Show Association With Femoral Instead of Abdominal Adipocyte Size in Asian Indians
por: Sahlot, Rahul, et al.
Publicado: (2021)

SUN-LB106 The Transcriptomic Evidences on Role of Abdominal Visceral vs. Subcutaneous Adipose Tissue in the Pathophysiology of Diabetes in Asian Indian Indicates the Involvement of Both
por: Mathur, Sandeep Kumar, et al.
Publicado: (2020)

The common pathophysiologic threads between Asian Indian diabetic’s ‘Thin Fat Phenotype’ and partial lipodystrophy: the peripheral adipose tissue transcriptomic evidences
por: Saxena, Aditya, et al.
Publicado: (2020)

MetaGen: reference-free learning with multiple metagenomic samples
por: Xing, Xin, et al.
Publicado: (2017)

Systems Genomics of Thigh Adipose Tissue From Asian Indian Type-2 Diabetics Revealed Distinct Protein Interaction Hubs
por: Tiwari, Pradeep, et al.
Publicado: (2019)

The Transcriptomic Evidence on the Role of Abdominal Visceral vs. Subcutaneous Adipose Tissue in the Pathophysiology of Diabetes in Asian Indians Indicates the Involvement of Both
por: Kumar, Anshul, et al.
Publicado: (2020)

Machine‐learning based radiogenomics analysis of MRI features and metagenes in glioblastoma multiforme patients with different survival time
por: Liao, Xin, et al.
Publicado: (2019)

Biomolecular Events in Cancer Revealed by Attractor Metagenes
por: Cheng, Wei-Yi, et al.
Publicado: (2013)

Microarray Evidences the Role of Pathologic Adipose Tissue in Insulin Resistance and Their Clinical Implications
por: Mathur, Sandeep Kumar, et al.
Publicado: (2011)

Metagenes Associated with Survival in Non-Small Cell Lung Cancer
por: Urgard, Egon, et al.
Publicado: (2011)

Functional Interactomes of Genes Showing Association with Type-2 Diabetes and Its Intermediate Phenotypic Traits Point towards Adipo-Centric Mechanisms in Its Pathophysiology
por: Saxena, Aditya, et al.
Publicado: (2020)

Prognostic signatures of breast cancer: Perou's molecular subtypes and Schmidt's metagenes
por: Cadenas, Cristina
Publicado: (2012)

Dual roles for immune metagenes in breast cancer prognosis and therapy prediction
por: Alistar, Angela, et al.
Publicado: (2014)

The MetaGens algorithm for metagenomic database lossy compression and subject alignment
por: Cervi, Gustavo Henrique, et al.
Publicado: (2023)

Genetics of Lipodystrophy: Can It Help in Understanding the Pathophysiology of Metabolic Syndrome?
por: Mathur, Sandeep Kumar, et al.
Publicado: (2018)

MetaGene: prokaryotic gene finding from environmental genome shotgun sequences
por: Noguchi, Hideki, et al.
Publicado: (2006)

metagene Profiles Analyses Reveal Regulatory Element’s Factor-Specific Recruitment Patterns
por: Joly Beauparlant, Charles, et al.
Publicado: (2016)

Hormone resistance and hypersensitivity: From genetics to clinical management
por: Mathur, Sandeep K.
Publicado: (2015)

Dissection of Genetic Basis Underpinning Kernel Weight-Related Traits in Common Wheat
por: Li, Shunda, et al.
Publicado: (2021)

CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies
por: Paananen, Jussi, et al.
Publicado: (2006)

Identification of metagenes and their Interactions through Large-scale Analysis of Arabidopsis Gene Expression Data
por: Wilson, Tyler J, et al.
Publicado: (2012)

DNA Repair Gene Expression Adjusted by the PCNA Metagene Predicts Survival in Multiple Cancers
por: Peterson, Leif E., et al.
Publicado: (2019)

Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response
por: Li, Qiyuan, et al.
Publicado: (2011)

Prediction of Breast Cancer Metastasis by Gene Expression Profiles: A Comparison of Metagenes and Single Genes
por: Burton, Mark, et al.
Publicado: (2012)

Machine learning applications using Python: cases studies from healthcare, retail, and finance
por: Mathur, Puneet
Publicado: (2019)

Transcriptome profiling reveals association of peripheral adipose tissue pathology with type-2 diabetes in Asian Indians
por: Saxena, Aditya, et al.
Publicado: (2019)

Effect of school-based educational water, sanitation, and hygiene intervention on student’s knowledge in a resource-limited setting
por: Mushota, Ommy, et al.
Publicado: (2021)

Can use of pictograms reduce liquid medication administration errors by mothers? An interventional study
por: Patidar, Pawan, et al.
Publicado: (2021)

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
por: Buffa, F M, et al.
Publicado: (2010)

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
por: Buffa, F M, et al.
Publicado: (2010)

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
por: Buffa, F M, et al.
Publicado: (2010)

Incidence and Risk Factors for Severe Pneumonia in Children Hospitalized with Pneumonia in Ujjain, India
por: Kasundriya, Sunil Kumar, et al.
Publicado: (2020)

IoT Machine Learning Applications in Telecom, Energy, and Agriculture: With Raspberry Pi and Arduino Using Python
por: Mathur, Puneet
Publicado: (2020)

The diagnostic and prognostic utility of insulin growth factor of squamous cell carcinoma in oral cavity
por: Tiwari, Sumit Kumar, et al.
Publicado: (2020)

Molecular and Metabolic Markers of Fructose Induced Hepatic Insulin Resistance in Developing and Adult Rats are Distinct and Aegle marmelos is an Effective Modulator
por: Nair, Jayachandran, et al.
Publicado: (2018)

Microbiome genetics underpins chemotherapy
por: Scott, Timothy A., et al.
Publicado: (2017)

Hypertension Association with Serum Lipoproteins, Insulin, Insulin Resistance and C–Peptide: Unexplored Forte of Cardiovascular Risk in Hypothyroidism
por: Purohit, Purvi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_5621452peuhfhoe90ug8qmbfhf