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Modulation of Allosteric Control and Evolution of Hemoglobin

Allostery arises when a ligand-induced change in shape of a binding site of a protein is coupled to a tertiary/quaternary conformational change with a consequent modulation of functional properties. The two-state allosteric model of Monod, Wyman and Changeux [J. Mol. Biol. 1965; 12, 88–118] is an el...

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Detalles Bibliográficos
Autores principales: Brunori, Maurizio, Miele, Adriana Erica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046315/
https://www.ncbi.nlm.nih.gov/pubmed/36979507
http://dx.doi.org/10.3390/biom13030572

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