Cargando…

Normal β-Cell Glut2 Expression Is not Required for Regulating Glucose-Stimulated Insulin Secretion and Systemic Glucose Homeostasis in Mice

Objective: Glucose transporter 2 (GLUT2) is expressed in the pancreatic β-cell, intestine, liver, and kidney in mice. Although GLUT2 is considered as a major regulator of insulin secretion, in vivo contribution of β-cell Glut2 to glucose-stimulated insulin secretion and systemic glucose homeostasis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bathina, Siresha, Faniyan, Tumininu S., Bainbridge, Lauren, Davis, Autumn, Chhabra, Kavaljit H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046365/ https://www.ncbi.nlm.nih.gov/pubmed/36979475 http://dx.doi.org/10.3390/biom13030540

Ejemplares similares

RF04 | PSUN298 Loss of β-Cell Glut2 Does Not Affect Systemic Glucose Homeostasis in Mice
por: Bathina, Siresha, et al.
Publicado: (2022)

THU123 Knockout Of Renal Glut2 Gene Activates The Hypothalamic-pituitary-adrenal Axis To Increase Glucose Production In Mice
por: Faniyan, Tumininu S, et al.
Publicado: (2023)

OR12-06 Hypothalamic Adgrl1 Is A Potential Glucoreceptor Involved In Regulating Energy Balance, Glucose Homeostasis, And Leptin Sensitivity In Mice
por: Samuel, Dennis J, et al.
Publicado: (2023)

A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria
por: Faniyan, Tumininu S., et al.
Publicado: (2023)

MON-639 Melanocortin 4 Receptor Contributes to Glucose Homeostasis by Regulating Kidney Glucose Reabsorption via the Glucose Transporter GLUT2
por: de Souza Cordeiro, Leticia M, et al.
Publicado: (2020)

Renal GLUT2 is Essential in Regulating Systemic Glucose Homeostasis by Glycosuria
por: de Souza Cordeiro, Leticia M, et al.
Publicado: (2021)

OR26-01 Epinephrine Is Essential for Normal Renal Glucose Reabsorption via the Glucose Transporter GLUT2
por: Elsheikh, Arwa Mahmoud, et al.
Publicado: (2020)

Insulin Stimulated-Glucose Transporter Glut 4 Is Expressed in the Retina
por: Sánchez-Chávez, Gustavo, et al.
Publicado: (2012)

Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake
por: Beg, Muheeb, et al.
Publicado: (2017)

LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol
por: Nøhr, Mark K., et al.
Publicado: (2016)

Comment on: Takeda et al. Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice. Diabetes 2013;62:223–233
por: Chhabra, Kavaljit H., et al.
Publicado: (2013)

An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice
por: Sadacca, L. A., et al.
Publicado: (2010)

Role of Vitamin D in Insulin Secretion and Insulin Sensitivity for Glucose Homeostasis
por: Alvarez, Jessica A., et al.
Publicado: (2010)

Regulation of GLUT4 and Insulin-Dependent Glucose Flux
por: Olson, Ann Louise
Publicado: (2012)

Loss of Sugar Detection by GLUT2 Affects Glucose Homeostasis in Mice
por: Stolarczyk, Emilie, et al.
Publicado: (2007)

Zinc Status Affects Glucose Homeostasis and Insulin Secretion in Patients with Thalassemia
por: Fung, Ellen B., et al.
Publicado: (2015)

Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis
por: Ma, Yue, et al.
Publicado: (2018)

SAT043 Chronically High Cerebrospinal Fluid Glucose Levels Impair Memory In Male Mice
por: Raza, Muhammad U, et al.
Publicado: (2023)

Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria
por: Chhabra, Kavaljit H., et al.
Publicado: (2016)

Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs
por: Goutchtat, Rébecca, et al.
Publicado: (2023)

Defective insulin-stimulated GLUT4 translocation in brown adipocytes induces systemic glucose homeostasis dysregulation independent of thermogenesis in female mice
por: Picatoste, Belén, et al.
Publicado: (2021)

Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans
por: Tong, Jenny, et al.
Publicado: (2010)

Aging Affects Insulin Resistance, Insulin Secretion, and Glucose Effectiveness in Subjects with Normal Blood Glucose and Body Weight
por: Huang, Li-Ying, et al.
Publicado: (2023)

Estimation of insulin secretion, glucose uptake by tissues, and liver handling of glucose using a mathematical model of glucose-insulin homeostasis in lean and obese mice
por: Brenner, Michael, et al.
Publicado: (2017)

The pore-forming subunit MCU of the mitochondrial Ca(2+) uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice
por: Georgiadou, Eleni, et al.
Publicado: (2020)

Hypothalamic Regulation of Glucose-Stimulated Insulin Secretion
por: Chan, Owen, et al.
Publicado: (2012)

Improved glucose tolerance with DPPIV inhibition requires β‐cell SENP1 amplification of glucose‐stimulated insulin secretion
por: Ferdaoussi, Mourad, et al.
Publicado: (2020)

Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis
por: Sumara, Grzegorz, et al.
Publicado: (2009)

SIRT5 is important for bacterial infection by regulating insulin secretion and glucose homeostasis
por: Zhang, Cuiping, et al.
Publicado: (2020)

Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion
por: Li, L, et al.
Publicado: (2016)

Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion
por: Salunkhe, Vishal A., et al.
Publicado: (2016)

A distinct role of STING in regulating glucose homeostasis through insulin sensitivity and insulin secretion
por: Qiao, Jingting, et al.
Publicado: (2022)

Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis
por: Collier, J. Jason, et al.
Publicado: (2020)

Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis
por: Schmitt, Charlotte C., et al.
Publicado: (2016)

EsGLUT4 and CHHBP are involved in the regulation of glucose homeostasis in the crustacean Eriocheir sinensis
por: Li, Ran, et al.
Publicado: (2017)

(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice
por: Zhang, Yu, et al.
Publicado: (2012)

Regional Variations of Insulin Secretion and Insulin Sensitivity in Japanese Participants With Normal Glucose Tolerance
por: Watanabe, Kiriko, et al.
Publicado: (2021)

An Insulin-Like Modular Basis for the Evolution of Glucose Transporters (GLUT) with Implications for Diabetes
por: Root-Bernstein, Robert
Publicado: (2007)

Development of Glucose Transporter (GLUT) Inhibitors
por: Reckzeh, Elena S., et al.
Publicado: (2019)

Glucose‐stimulated insulin secretion: A newer perspective
por: Komatsu, Mitsuhisa, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7e5asjqq3se9r4go3l3pvim2jh