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Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat
The worldwide increase in cognitive decline, both in aging and with psychiatric disorders, warrants a search for pharmacological treatment. Although dopaminergic treatment approaches represent a major step forward, current dopamine transporter (DAT) inhibitors are not sufficiently specific as they a...
Autores principales: | Lubec, Jana, Hussein, Ahmed M., Kalaba, Predrag, Feyissa, Daniel Daba, Arias-Sandoval, Edgar, Cybulska-Klosowicz, Anita, Bezu, Mekite, Stojanovic, Tamara, Korz, Volker, Malikovic, Jovana, Aher, Nilima Y., Zehl, Martin, Dragacevic, Vladimir, Leban, Johann Jakob, Sagheddu, Claudia, Wackerlig, Judith, Pistis, Marco, Correa, Merce, Langer, Thierry, Urban, Ernst, Höger, Harald, Lubec, Gert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046369/ https://www.ncbi.nlm.nih.gov/pubmed/36979402 http://dx.doi.org/10.3390/biom13030467 |
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