Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane

The activation of G Protein-Coupled Receptor 56 (GPR56), also referred to as Adhesion G-Protein-Coupled Ceceptor G1 (ADGRG1), by Collagen Type III (Coll III) prompts cell growth, proliferation, and survival, among other attributes. We investigated the signaling cascades mediating this functional eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohammad Al-Amily, Israa, Sjögren, Marie, Duner, Pontus, Tariq, Mohammad, Wollheim, Claes B., Salehi, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046417/
https://www.ncbi.nlm.nih.gov/pubmed/36979492
http://dx.doi.org/10.3390/biom13030557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046417/
https://www.ncbi.nlm.nih.gov/pubmed/36979492
http://dx.doi.org/10.3390/biom13030557

Ejemplares similares