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Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane
The activation of G Protein-Coupled Receptor 56 (GPR56), also referred to as Adhesion G-Protein-Coupled Ceceptor G1 (ADGRG1), by Collagen Type III (Coll III) prompts cell growth, proliferation, and survival, among other attributes. We investigated the signaling cascades mediating this functional eff...
Autores principales: | Mohammad Al-Amily, Israa, Sjögren, Marie, Duner, Pontus, Tariq, Mohammad, Wollheim, Claes B., Salehi, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046417/ https://www.ncbi.nlm.nih.gov/pubmed/36979492 http://dx.doi.org/10.3390/biom13030557 |
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