The Absence of Gasdermin D Reduces Nuclear Autophagy in a Cecal Ligation and Puncture-Induced Sepsis-Associated Encephalopathy Mouse Model

Sepsis-associated encephalopathy (SAE) is a common complication of sepsis, which is a life-threatening condition resulting from a dysregulated host response to infection. Pyroptosis, a pro-inflammatory mode of lytic cell death mediated by GSDMD (Gasdermin D), is involved in the pathogenesis of SAE....

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Detalles Bibliográficos
Autores principales: Su, Wei, Xie, Zhenxing, Bai, Xiangjun, Li, Zhanfei, Liu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046561/
https://www.ncbi.nlm.nih.gov/pubmed/36979288
http://dx.doi.org/10.3390/brainsci13030478

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