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The Tryptophan-Kynurenine Metabolic System Is Suppressed in Cuprizone-Induced Model of Demyelination Simulating Progressive Multiple Sclerosis

Progressive multiple sclerosis (MS) is a chronic disease with a unique pattern, which is histologically classified into the subpial type 3 lesions in the autopsy. The lesion is also homologous to that of cuprizone (CPZ) toxin-induced animal models of demyelination. Aberration of the tryptophan (TRP)...

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Detalles Bibliográficos
Autores principales:	Polyák, Helga, Galla, Zsolt, Nánási, Nikolett, Cseh, Edina Katalin, Rajda, Cecília, Veres, Gábor, Spekker, Eleonóra, Szabó, Ágnes, Klivényi, Péter, Tanaka, Masaru, Vécsei, László
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046567/ https://www.ncbi.nlm.nih.gov/pubmed/36979924 http://dx.doi.org/10.3390/biomedicines11030945

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