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Improving the Accuracy of Single-Nucleotide Variant Diagnosis Using On–Off Discriminating Primers
Early detection of rare mutations through liquid biopsy can provide real-time information related to cancer diagnosis, prognosis, and treatment outcomes. Cell-free DNA samples used in liquid biopsies contain single-nucleotide variants (SNVs) with a variant allele frequency (VAF) of approximately ≤1%...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046569/ https://www.ncbi.nlm.nih.gov/pubmed/36979592 http://dx.doi.org/10.3390/bios13030380 |