Target Antigen Attributes and Their Contributions to Clinically Approved Antibody-Drug Conjugates (ADCs) in Haematopoietic and Solid Cancers

SIMPLE SUMMARY: Antibody-Drug Conjugates (ADCs) provide effective anti-cancer treatments. ADC development requires the identification of appropriate tumour-associated antigens that can be targeted by the ADC to effectively kill cancer cells while minimising damage to healthy cells, thus limiting sys...

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Detalles Bibliográficos
Autores principales: Esapa, Benjamina, Jiang, Jiexuan, Cheung, Anthony, Chenoweth, Alicia, Thurston, David E., Karagiannis, Sophia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046624/
https://www.ncbi.nlm.nih.gov/pubmed/36980732
http://dx.doi.org/10.3390/cancers15061845

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