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Peptide-Based siRNA Nanocomplexes Targeting Hepatic Stellate Cells

Liver fibrosis is the excessive accumulation of extracellular matrix (ECM) in the liver due to chronic injuries and inflammation. These injuries activate and transform quiescent hepatic stellate cells (HSCs) into proliferative myofibroblast-like cells, which are the key contributors to the secretin...

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Detalles Bibliográficos
Autores principales: Lin, Chien-Yu, Mamani, Umar-Farouk, Guo, Yuhan, Liu, Yanli, Cheng, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046633/
https://www.ncbi.nlm.nih.gov/pubmed/36979383
http://dx.doi.org/10.3390/biom13030448