T Cell Immunoglobulin and Mucin Domain 3 (TIM-3) in Cutaneous Melanoma: A Narrative Review

SIMPLE SUMMARY: T cell immunoglobulin and mucin domain 3 (TIM-3) is an inhibitory immunocheckpoint expressed on cytotoxic CD8+ T lymphocytes, NK cells, and myeloid lineage cells in addition to Th1 lymphocytes. Various studies have investigated its role within the tumour microenvironment of melanoma,...

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Detalles Bibliográficos
Autores principales: Cazzato, Gerardo, Cascardi, Eliano, Colagrande, Anna, Lettini, Teresa, Filosa, Alessandra, Arezzo, Francesca, Lupo, Carmelo, Casatta, Nadia, Loizzi, Vera, Pellegrini, Cristina, Fargnoli, Maria Concetta, Maiorano, Eugenio, Cicco, Gerolamo, Tamma, Roberto, Ingravallo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046653/
https://www.ncbi.nlm.nih.gov/pubmed/36980583
http://dx.doi.org/10.3390/cancers15061697

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