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Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors

OBJECTIVE: The aim of this study was to evaluate our institutional experience with the combined transoral plus lateral pharyngotomy (TO+LP) approach in a subset of patients with advanced or recurrent oral and oropharyngeal malignancy. STUDY DESIGN: A retrospective study of procedures utilizing TO+LP...

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Autores principales: Colevas, Sophia M., Merfeld, Emily C., Pflum, Zachary E., Gessert, Thomas G., Wieland, Aaron M., Glazer, Tiffany A., Burr, Adam R., Harari, Paul M., Hartig, Gregory K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046711/
https://www.ncbi.nlm.nih.gov/pubmed/36998565
http://dx.doi.org/10.1002/oto2.35
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author Colevas, Sophia M.
Merfeld, Emily C.
Pflum, Zachary E.
Gessert, Thomas G.
Wieland, Aaron M.
Glazer, Tiffany A.
Burr, Adam R.
Harari, Paul M.
Hartig, Gregory K.
author_facet Colevas, Sophia M.
Merfeld, Emily C.
Pflum, Zachary E.
Gessert, Thomas G.
Wieland, Aaron M.
Glazer, Tiffany A.
Burr, Adam R.
Harari, Paul M.
Hartig, Gregory K.
author_sort Colevas, Sophia M.
collection PubMed
description OBJECTIVE: The aim of this study was to evaluate our institutional experience with the combined transoral plus lateral pharyngotomy (TO+LP) approach in a subset of patients with advanced or recurrent oral and oropharyngeal malignancy. STUDY DESIGN: A retrospective study of procedures utilizing TO+LP for cancer resection between January 2007 and July 2019. SETTING: Tertiary academic medical center. METHODS: Thirty‐one patients underwent a TO+LP approach for the resection of oral and oropharyngeal tumors. Functional and oncologic outcomes were analyzed. RESULTS: Eighteen (58.1%) patients were treated with TO+LP for recurrent disease. Twenty‐nine required free tissue transfer and 2 (6.5%) had positive margins. The median time to decannulation was 22 days (range 6‐100 days). Thirteen (41.9%) patients still required enteral feeding at their most recent follow‐up. Patients without a history of prior radiation were decannulated sooner (p = .009) and were less likely to require enteral feeding at the first postoperative follow‐up (p = .034) than those who had prior head and neck radiotherapy. CONCLUSION: A TO+LP approach can be used to achieve good functional and oncologic results for selected patients with advanced or recurrent oral and oropharyngeal cancer when minimally invasive options such as transoral robotic surgery, transoral laser microsurgery, or radiotherapy are not possible.
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spelling pubmed-100467112023-03-29 Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors Colevas, Sophia M. Merfeld, Emily C. Pflum, Zachary E. Gessert, Thomas G. Wieland, Aaron M. Glazer, Tiffany A. Burr, Adam R. Harari, Paul M. Hartig, Gregory K. OTO Open Original Research OBJECTIVE: The aim of this study was to evaluate our institutional experience with the combined transoral plus lateral pharyngotomy (TO+LP) approach in a subset of patients with advanced or recurrent oral and oropharyngeal malignancy. STUDY DESIGN: A retrospective study of procedures utilizing TO+LP for cancer resection between January 2007 and July 2019. SETTING: Tertiary academic medical center. METHODS: Thirty‐one patients underwent a TO+LP approach for the resection of oral and oropharyngeal tumors. Functional and oncologic outcomes were analyzed. RESULTS: Eighteen (58.1%) patients were treated with TO+LP for recurrent disease. Twenty‐nine required free tissue transfer and 2 (6.5%) had positive margins. The median time to decannulation was 22 days (range 6‐100 days). Thirteen (41.9%) patients still required enteral feeding at their most recent follow‐up. Patients without a history of prior radiation were decannulated sooner (p = .009) and were less likely to require enteral feeding at the first postoperative follow‐up (p = .034) than those who had prior head and neck radiotherapy. CONCLUSION: A TO+LP approach can be used to achieve good functional and oncologic results for selected patients with advanced or recurrent oral and oropharyngeal cancer when minimally invasive options such as transoral robotic surgery, transoral laser microsurgery, or radiotherapy are not possible. John Wiley and Sons Inc. 2023-02-23 /pmc/articles/PMC10046711/ /pubmed/36998565 http://dx.doi.org/10.1002/oto2.35 Text en © 2023 The Authors. OTO Open published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngology–Head and Neck Surgery Foundation. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Colevas, Sophia M.
Merfeld, Emily C.
Pflum, Zachary E.
Gessert, Thomas G.
Wieland, Aaron M.
Glazer, Tiffany A.
Burr, Adam R.
Harari, Paul M.
Hartig, Gregory K.
Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors
title Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors
title_full Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors
title_fullStr Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors
title_full_unstemmed Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors
title_short Functional Outcomes After Transoral Plus Lateral Pharyngotomy Approach for Advanced Oral and Oropharyngeal Tumors
title_sort functional outcomes after transoral plus lateral pharyngotomy approach for advanced oral and oropharyngeal tumors
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046711/
https://www.ncbi.nlm.nih.gov/pubmed/36998565
http://dx.doi.org/10.1002/oto2.35
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