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Role and Potential of Different T Helper Cell Subsets in Adoptive Cell Therapy

SIMPLE SUMMARY: While most cancer immunotherapies have focused on CD8(+) T cells as the main drivers of antitumor immunity, increasing evidence indicates that CD4(+) T cells also play a central role in the elimination of tumors. Naïve CD4 T cells can be polarized towards different helper subsets, wh...

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Detalles Bibliográficos
Autores principales: Andreu-Sanz, David, Kobold, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046829/
https://www.ncbi.nlm.nih.gov/pubmed/36980536
http://dx.doi.org/10.3390/cancers15061650