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Nanobodies Selectively Binding to the Idiotype of a Dengue Virus Neutralizing Antibody Do Not Necessarily Mimic the Viral Epitope

Vaccination against dengue virus is challenged by the fact that a generic immune response can induce antibody-dependent-enhancement (ADE) in secondary infections. Only some antibodies targeting a quaternary epitope formed by the dimerization of the virus protein E possess sufficient neutralizing cap...

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Detalles Bibliográficos
Autores principales:	Poggianella, Monica, Bernedo, Robert, Oloketuyi, Sandra, de Marco, Ario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046864/ https://www.ncbi.nlm.nih.gov/pubmed/36979486 http://dx.doi.org/10.3390/biom13030551

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