B7H4 Expression Is More Frequent in MSS Status Colorectal Cancer and Is Negatively Associated with Tumour Infiltrating Lymphocytes

The immunotherapies based on ICIs in CRC are nowadays limited to microsatellite unstable tumours which are approximately 15% of all CRC cases. There are a few new immune checkpoints belonging to the B7 family, including B7H4. B7H4 expression is associated with so-called “cold tumours”, and its funct...

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Detalles Bibliográficos
Autores principales: Dawidowicz, Miriam, Kula, Agnieszka, Mielcarska, Sylwia, Kiczmer, Paweł, Skiba, Hanna, Krygier, Małgorzata, Chrabańska, Magdalena, Piecuch, Jerzy, Szrot, Monika, Robotycka, Julia, Ochman, Błażej, Strzałkowska, Bogumiła, Czuba, Zenon, Świętochowska, Elżbieta, Waniczek, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046962/
https://www.ncbi.nlm.nih.gov/pubmed/36980202
http://dx.doi.org/10.3390/cells12060861

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