Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3

Acute kidney injury (AKI) leads to acute cardiac injury and dysfunction in cardiorenal syndrome Type 3 (CRS3) through oxidative stress (OS). The stress-inducible Sestrin2 (Sesn2) protein reduces reactive oxygen species (ROS) accumulation and activates AMP-dependent protein kinase (AMPK) to regulate...

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Detalles Bibliográficos
Autores principales: Iglesias, Migdalia, Wang, Hao, Krause-Hauch, Meredith, Ren, Di, Zoungrana, Linda Ines, Li, Zehui, Zhang, Jie, Wei, Jin, Yadav, Nikita, Patel, Kshama, Fatmi, Mohammad Kasim, Liu, Ruisheng, Lesnefsky, Edward J., Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047033/
https://www.ncbi.nlm.nih.gov/pubmed/36980186
http://dx.doi.org/10.3390/cells12060845

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