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Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors

Resection of lung metastases in children with solid tumors is regularly hampered by limited intraoperative detectability and relevant operative trauma of the open surgical access. The aim of this study was to analyze thoracoscopic resection of lung metastases in children following CT-guided labeling...

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Autores principales: Warmann, Steven W., Lieber, Justus, Schaefer, Juergen F., Ebinger, Martin, Urla, Cristian, Kirschner, Hans-Joachim, Tsiflikas, Ilias, Schmidt, Andreas, Fuchs, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047192/
https://www.ncbi.nlm.nih.gov/pubmed/36980100
http://dx.doi.org/10.3390/children10030542
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author Warmann, Steven W.
Lieber, Justus
Schaefer, Juergen F.
Ebinger, Martin
Urla, Cristian
Kirschner, Hans-Joachim
Tsiflikas, Ilias
Schmidt, Andreas
Fuchs, Joerg
author_facet Warmann, Steven W.
Lieber, Justus
Schaefer, Juergen F.
Ebinger, Martin
Urla, Cristian
Kirschner, Hans-Joachim
Tsiflikas, Ilias
Schmidt, Andreas
Fuchs, Joerg
author_sort Warmann, Steven W.
collection PubMed
description Resection of lung metastases in children with solid tumors is regularly hampered by limited intraoperative detectability and relevant operative trauma of the open surgical access. The aim of this study was to analyze thoracoscopic resection of lung metastases in children following CT-guided labeling with coil wires. We retrospectively analyzed data of children and adolescents undergoing this approach at our institution between 2010 and 2022 with regard to technical aspects as well as surgical and oncological data. Within this period, we performed this procedure on 12 patients wherein we resected 18 lesions (1–5 per patient). The median age of patients was 178 months (51–265). The median duration of coil wire placement was 41 min (30–173) and the median surgery time was 53 min (11–157). No conversions were necessary and no intraoperative complications occurred. Complete microscopic resection (R0) was achieved in all labeled lesions and malignant tumor components were found in 5/12 patients. Our study shows that with a careful patient selection, thoracoscopic resection of lung metastases after coil wire labeling is a safe and reproducible procedure in children. Using this approach, lesions that are expected to have a reduced intraoperative detectability during open surgery become resectable. Patients benefit from the minimally invasive surgical access and reduced operative trauma.
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spelling pubmed-100471922023-03-29 Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors Warmann, Steven W. Lieber, Justus Schaefer, Juergen F. Ebinger, Martin Urla, Cristian Kirschner, Hans-Joachim Tsiflikas, Ilias Schmidt, Andreas Fuchs, Joerg Children (Basel) Article Resection of lung metastases in children with solid tumors is regularly hampered by limited intraoperative detectability and relevant operative trauma of the open surgical access. The aim of this study was to analyze thoracoscopic resection of lung metastases in children following CT-guided labeling with coil wires. We retrospectively analyzed data of children and adolescents undergoing this approach at our institution between 2010 and 2022 with regard to technical aspects as well as surgical and oncological data. Within this period, we performed this procedure on 12 patients wherein we resected 18 lesions (1–5 per patient). The median age of patients was 178 months (51–265). The median duration of coil wire placement was 41 min (30–173) and the median surgery time was 53 min (11–157). No conversions were necessary and no intraoperative complications occurred. Complete microscopic resection (R0) was achieved in all labeled lesions and malignant tumor components were found in 5/12 patients. Our study shows that with a careful patient selection, thoracoscopic resection of lung metastases after coil wire labeling is a safe and reproducible procedure in children. Using this approach, lesions that are expected to have a reduced intraoperative detectability during open surgery become resectable. Patients benefit from the minimally invasive surgical access and reduced operative trauma. MDPI 2023-03-12 /pmc/articles/PMC10047192/ /pubmed/36980100 http://dx.doi.org/10.3390/children10030542 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Warmann, Steven W.
Lieber, Justus
Schaefer, Juergen F.
Ebinger, Martin
Urla, Cristian
Kirschner, Hans-Joachim
Tsiflikas, Ilias
Schmidt, Andreas
Fuchs, Joerg
Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors
title Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors
title_full Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors
title_fullStr Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors
title_full_unstemmed Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors
title_short Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors
title_sort thoracoscopic resection of lung nodules following ct-guided labeling in children and adolescents with solid tumors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047192/
https://www.ncbi.nlm.nih.gov/pubmed/36980100
http://dx.doi.org/10.3390/children10030542
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