Cargando…
Computational and Functional Analysis of Structural Features in the ZAKα Kinase
The kinase ZAKα acts as the proximal sensor of translational impairment and ribotoxic stress, which results in the activation of the MAP kinases p38 and JNK. Despite recent insights into the functions and binding partners of individual protein domains in ZAKα, the mechanisms by which ZAKα binds ribo...
Autores principales: | Johansen, Valdemar Brimnes Ingemann, Snieckute, Goda, Vind, Anna Constance, Blasius, Melanie, Bekker-Jensen, Simon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047201/ https://www.ncbi.nlm.nih.gov/pubmed/36980309 http://dx.doi.org/10.3390/cells12060969 |
Ejemplares similares
-
Initiation of a ZAKα-dependent Ribotoxic Stress Response by the Innate Immunity Endoribonuclease RNase L
por: Xi, Jiajia, et al.
Publicado: (2023) -
ZAKβ is activated by cellular compression and mediates contraction‐induced MAP kinase signaling in skeletal muscle
por: Nordgaard, Cathrine, et al.
Publicado: (2022) -
The Impact of Dietary Factors during Pregnancy on the Development of Islet Autoimmunity and Type 1 Diabetes: A Systematic Literature Review
por: Johansen, Valdemar Brimnes Ingemann, et al.
Publicado: (2023) -
Nitric oxide-induced ribosome collision activates ribosomal surveillance mechanisms
por: Ryder, Laura, et al.
Publicado: (2023) -
ZAKα/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome
por: Rodríguez‐Ruiz, Lola, et al.
Publicado: (2023)