Cargando…

Frequency of Peripheral CD8+ T Cells Expressing Chemo-Attractant Receptors CCR1, 4 and 5 Increases in NPC Patients with EBV Clearance upon Radiotherapy

SIMPLE SUMMARY: The post-radiotherapy (RT) clearance of tumor-derived plasma EBV DNA is associated with a better prognosis in patients with nasopharyngeal cancer (NPC). T cells may play a critical role in the clearance of plasma EBV DNA in NPC. We explored the dynamic changes in circulating T-cell p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mahajan, Shweta, Balcioglu, Hayri E., Oostvogels, Astrid, Dik, Willem A., Chan, K. C. Allen, Lo, Kwok-Wai, Hui, Edwin P., Tsang, Anna, Tong, Joanna, Lam, Wai Kei Jacky, Wong, Kenneth, Chan, Anthony T. C., Ma, Brigette B. Y., Debets, Reno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047204/ https://www.ncbi.nlm.nih.gov/pubmed/36980772 http://dx.doi.org/10.3390/cancers15061887

Ejemplares similares

The Role of NK Cells in EBV Infection and EBV-Associated NPC
por: Png, Yi Tian, et al.
Publicado: (2021)

Emodin Inhibits EBV Reactivation and Represses NPC Tumorigenesis
por: Wu, Chung-Chun, et al.
Publicado: (2019)

Curdlan, zymosan and a yeast-derived β-glucan reshape tumor-associated macrophages into producers of inflammatory chemo-attractants
por: de Graaff, Priscilla, et al.
Publicado: (2020)

Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens
por: Weenink, Bas, et al.
Publicado: (2019)

EBV reactivation as a target of luteolin to repress NPC tumorigenesis
por: Wu, Chung-Chun, et al.
Publicado: (2016)

CD45RA(+)CCR7(−) CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab
por: Kunert, Andre, et al.
Publicado: (2019)

The Role of EBV-Encoded LMP1 in the NPC Tumor Microenvironment: From Function to Therapy
por: Lo, Angela Kwok-Fung, et al.
Publicado: (2021)

Prognostication of Half-Life Clearance of Plasma EBV DNA in Previously Untreated Non-metastatic Nasopharyngeal Carcinoma Treated With Radical Intensity-Modulated Radiation Therapy
por: Chan, Sik-Kwan, et al.
Publicado: (2020)

Molecular screening for Epstein Barr virus (EBV) among Sudanese patients with nasopharyngeal carcinoma (NPC)
por: Ahmed, Hussain Gadelkarim, et al.
Publicado: (2015)

Intratumoral Niches of B Cells and Follicular Helper T Cells, and the Absence of Regulatory T Cells, Associate with Longer Survival in Early-Stage Oral Tongue Cancer Patients
por: Phanthunane, Chumut, et al.
Publicado: (2022)

V-Domain Ig Suppressor of T Cell Activation (VISTA) Expression Is an Independent Prognostic Factor in Multiple Myeloma
por: Mutsaers, Pim, et al.
Publicado: (2021)

F factor plasmid-mediated Epstein-Barr virus genome introduction establishes an EBV positive NPC cell model
por: Duan, Jingling, et al.
Publicado: (2019)

A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer
por: Rijnders, Maud, et al.
Publicado: (2022)

The NPC, in detail
por: Robinson, Richard
Publicado: (2007)

Identification of an LPS-Induced Chemo-Attractive Peptide from Ciona robusta
por: Longo, Valeria, et al.
Publicado: (2020)

Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy
por: Liu, Wai Nam, et al.
Publicado: (2020)

Identification and Classification of Rare Variants in NPC1 and NPC2 in Quebec
por: Touma, Lahoud, et al.
Publicado: (2021)

Cancer-Associated Fibroblasts as Players in Cancer Development and Progression and Their Role in Targeted Radionuclide Imaging and Therapy
por: Koustoulidou, Sofia, et al.
Publicado: (2021)

A novel approach in predicting virtual garment fitting sizes with psychographic characteristics and 3D body measurements using artificial neural network and visualizing fitted bodies using generative adversarial network()
por: Dik, Nga Yin, et al.
Publicado: (2023)

Building and breaking the NPC
por: LeBrasseur, Nicole
Publicado: (2003)

Development of a risk classification system combining TN-categories and circulating EBV DNA for non-metastatic NPC in 10,149 endemic cases
por: Chen, Fo-Ping, et al.
Publicado: (2021)

Functional and Structural Plasticity of Brain in Elite Karate Athletes
por: Duru, Adil Deniz, et al.
Publicado: (2018)

Differential quantities of immune checkpoint-expressing CD8 T cells in soft tissue sarcoma subtypes
por: Klaver, Yarne, et al.
Publicado: (2020)

Single Agent and Synergistic Activity of Maritoclax with ABT-263 in Nasopharyngeal Carcinoma (NPC) Cell Lines
por: Xiang, Benedict Lian Shi, et al.
Publicado: (2020)

CC Chemokine Receptor (CCR)4 and the CCR10 Ligand Cutaneous T Cell–attracting Chemokine (CTACK) in Lymphocyte Trafficking to Inflamed Skin
por: Reiss, Yvonne, et al.
Publicado: (2001)

CD40L-adjuvanted DNA vaccine carrying EBV-LMP2 antigen enhances anti-tumor effect in NPC transplantation tumor animal
por: Lei, Lei, et al.
Publicado: (2018)

Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC
por: Zuo, Lielian, et al.
Publicado: (2019)

Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis
por: Li, Deng-Ke, et al.
Publicado: (2022)

Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer
por: Hammerl, Dora, et al.
Publicado: (2021)

Going their own way in the NPC
por: Leslie, Mitch
Publicado: (2007)

Simulations of NPC1(NTD):NPC2 Protein Complex Reveal Cholesterol Transfer Pathways
por: Hodošček, Milan, et al.
Publicado: (2018)

EBV–encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1
por: Lung, Raymond Wai‐Ming, et al.
Publicado: (2020)

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer
por: Ngan, Hoi-Lam, et al.
Publicado: (2018)

Leukocyte Attraction by CCL20 and Its Receptor CCR6 in Humans and Mice with Pneumococcal Meningitis
por: Klein, Matthias, et al.
Publicado: (2014)

Niemann-Pick C1 (NPC1)/NPC1-like1 Chimeras Define Sequences Critical for NPC1’s Function as a Filovirus Entry Receptor
por: Krishnan, Anuja, et al.
Publicado: (2012)

Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins
por: Saha, Piyali, et al.
Publicado: (2020)

Targeting exosomes enveloped EBV‐miR‐BART1‐5p‐antagomiRs for NPC therapy through both anti‐vasculogenic mimicry and anti‐angiogenesis
por: Wang, Jianguo, et al.
Publicado: (2023)

Prognostication of serial post-intensity-modulated radiation therapy undetectable plasma EBV DNA for nasopharyngeal carcinoma
por: Lee, Victor Ho-Fun, et al.
Publicado: (2016)

A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation
por: Chan, King Chi, et al.
Publicado: (2013)

CCR5del32 genotype in human enteroviral cardiomyopathy leads to spontaneous virus clearance and improved outcome compared to wildtype CCR5
por: Lassner, Dirk, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8b0bckg90slrn4ntuenu80m3pq