The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor

Syndecan-1 (Sdc-1) upregulation is associated with poor prognosis in breast cancer. Sdc-1 knockdown results in reduced angiogenesis and the dysregulation of tissue factor (TF) pathway constituents. Here, we evaluate the regulatory mechanisms and functional consequences of the Sdc-1/TF-axis using Sdc...

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Detalles Bibliográficos
Autores principales: Hassan, Nourhan, Bückreiß, Nico, Efing, Janes, Schulz-Fincke, Marie, König, Philipp, Greve, Burkhard, Bendas, Gerd, Götte, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047229/
https://www.ncbi.nlm.nih.gov/pubmed/36980251
http://dx.doi.org/10.3390/cells12060910

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