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Understanding the Combined Effects of High Glucose Induced Hyper-Osmotic Stress and Oxygen Tension in the Progression of Tumourigenesis: From Mechanism to Anti-Cancer Therapeutics

High glucose (HG), a hallmark of the tumour microenvironment, is also a biomechanical stressor, as it exerts hyper-osmotic stress (HG-HO), but not much is known regarding how tumour cells mechanoadapt to HG-HO. Therefore, this study aimed to delineate the novel molecular mechanisms by which tumour c...

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Detalles Bibliográficos
Autores principales: G., Gayathri K., Shinde, Puja Laxmanrao, John, Sebastian, C., Sivakumar K., Mishra, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047272/
https://www.ncbi.nlm.nih.gov/pubmed/36980166
http://dx.doi.org/10.3390/cells12060825