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Validation of an ICH Q2 Compliant Flow Cytometry-Based Assay for the Assessment of the Inhibitory Potential of Mesenchymal Stromal Cells on T Cell Proliferation

Mesenchymal stromal cells (MSCs) have the potential to suppress pathological activation of immune cells and have therefore been considered for the treatment of Graft-versus-Host-Disease. The clinical application of MSCs requires a process validation to ensure consistent quality. A flow cytometry-bas...

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Detalles Bibliográficos
Autores principales:	Piede, Natascha, Bremm, Melanie, Farken, Anne, Pfeffermann, Lisa-Marie, Cappel, Claudia, Bonig, Halvard, Fingerhut, Theres, Puth, Laura, Vogelsang, Kathrin, Peinelt, Andreas, Marschalek, Rolf, Müller, Matthias, Bader, Peter, Kuçi, Zyrafete, Kuçi, Selim, Huenecke, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047294/ https://www.ncbi.nlm.nih.gov/pubmed/36980191 http://dx.doi.org/10.3390/cells12060850

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