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Hindcasts and forecasts of suicide mortality in US: A modeling study

Deaths by suicide, as well as suicidal ideations, plans and attempts, have been increasing in the US for the past two decades. Deployment of effective interventions would require timely, geographically well-resolved estimates of suicide activity. In this study, we evaluated the feasibility of a two-...

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Autores principales: Kandula, Sasikiran, Olfson, Mark, Gould, Madelyn S., Keyes, Katherine M., Shaman, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047563/
https://www.ncbi.nlm.nih.gov/pubmed/36913441
http://dx.doi.org/10.1371/journal.pcbi.1010945
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author Kandula, Sasikiran
Olfson, Mark
Gould, Madelyn S.
Keyes, Katherine M.
Shaman, Jeffrey
author_facet Kandula, Sasikiran
Olfson, Mark
Gould, Madelyn S.
Keyes, Katherine M.
Shaman, Jeffrey
author_sort Kandula, Sasikiran
collection PubMed
description Deaths by suicide, as well as suicidal ideations, plans and attempts, have been increasing in the US for the past two decades. Deployment of effective interventions would require timely, geographically well-resolved estimates of suicide activity. In this study, we evaluated the feasibility of a two-step process for predicting suicide mortality: a) generation of hindcasts, mortality estimates for past months for which observational data would not have been available if forecasts were generated in real-time; and b) generation of forecasts with observational data augmented with hindcasts. Calls to crisis hotline services and online queries to the Google search engine for suicide-related terms were used as proxy data sources to generate hindcasts. The primary hindcast model (auto) is an Autoregressive Integrated Moving average model (ARIMA), trained on suicide mortality rates alone. Three regression models augment hindcast estimates from auto with call rates (calls), GHT search rates (ght) and both datasets together (calls_ght). The 4 forecast models used are ARIMA models trained with corresponding hindcast estimates. All models were evaluated against a baseline random walk with drift model. Rolling monthly 6-month ahead forecasts for all 50 states between 2012 and 2020 were generated. Quantile score (QS) was used to assess the quality of the forecast distributions. Median QS for auto was better than baseline (0.114 vs. 0.21. Median QS of augmented models were lower than auto, but not significantly different from each other (Wilcoxon signed-rank test, p > .05). Forecasts from augmented models were also better calibrated. Together, these results provide evidence that proxy data can address delays in release of suicide mortality data and improve forecast quality. An operational forecast system of state-level suicide risk may be feasible with sustained engagement between modelers and public health departments to appraise data sources and methods as well as to continuously evaluate forecast accuracy.
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spelling pubmed-100475632023-03-29 Hindcasts and forecasts of suicide mortality in US: A modeling study Kandula, Sasikiran Olfson, Mark Gould, Madelyn S. Keyes, Katherine M. Shaman, Jeffrey PLoS Comput Biol Research Article Deaths by suicide, as well as suicidal ideations, plans and attempts, have been increasing in the US for the past two decades. Deployment of effective interventions would require timely, geographically well-resolved estimates of suicide activity. In this study, we evaluated the feasibility of a two-step process for predicting suicide mortality: a) generation of hindcasts, mortality estimates for past months for which observational data would not have been available if forecasts were generated in real-time; and b) generation of forecasts with observational data augmented with hindcasts. Calls to crisis hotline services and online queries to the Google search engine for suicide-related terms were used as proxy data sources to generate hindcasts. The primary hindcast model (auto) is an Autoregressive Integrated Moving average model (ARIMA), trained on suicide mortality rates alone. Three regression models augment hindcast estimates from auto with call rates (calls), GHT search rates (ght) and both datasets together (calls_ght). The 4 forecast models used are ARIMA models trained with corresponding hindcast estimates. All models were evaluated against a baseline random walk with drift model. Rolling monthly 6-month ahead forecasts for all 50 states between 2012 and 2020 were generated. Quantile score (QS) was used to assess the quality of the forecast distributions. Median QS for auto was better than baseline (0.114 vs. 0.21. Median QS of augmented models were lower than auto, but not significantly different from each other (Wilcoxon signed-rank test, p > .05). Forecasts from augmented models were also better calibrated. Together, these results provide evidence that proxy data can address delays in release of suicide mortality data and improve forecast quality. An operational forecast system of state-level suicide risk may be feasible with sustained engagement between modelers and public health departments to appraise data sources and methods as well as to continuously evaluate forecast accuracy. Public Library of Science 2023-03-13 /pmc/articles/PMC10047563/ /pubmed/36913441 http://dx.doi.org/10.1371/journal.pcbi.1010945 Text en © 2023 Kandula et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kandula, Sasikiran
Olfson, Mark
Gould, Madelyn S.
Keyes, Katherine M.
Shaman, Jeffrey
Hindcasts and forecasts of suicide mortality in US: A modeling study
title Hindcasts and forecasts of suicide mortality in US: A modeling study
title_full Hindcasts and forecasts of suicide mortality in US: A modeling study
title_fullStr Hindcasts and forecasts of suicide mortality in US: A modeling study
title_full_unstemmed Hindcasts and forecasts of suicide mortality in US: A modeling study
title_short Hindcasts and forecasts of suicide mortality in US: A modeling study
title_sort hindcasts and forecasts of suicide mortality in us: a modeling study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047563/
https://www.ncbi.nlm.nih.gov/pubmed/36913441
http://dx.doi.org/10.1371/journal.pcbi.1010945
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