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Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images

Bone malignant tumors are metastatic and aggressive. The manual screening of medical images is time-consuming and laborious, and computer technology is now being introduced to aid in diagnosis. Due to a large amount of noise and blurred lesion edges in osteosarcoma MRI images, high-precision segment...

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Autores principales: Lv, Baolong, Liu, Feng, Li, Yulin, Nie, Jianhua, Gou, Fangfang, Wu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047640/
https://www.ncbi.nlm.nih.gov/pubmed/36980371
http://dx.doi.org/10.3390/diagnostics13061063
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author Lv, Baolong
Liu, Feng
Li, Yulin
Nie, Jianhua
Gou, Fangfang
Wu, Jia
author_facet Lv, Baolong
Liu, Feng
Li, Yulin
Nie, Jianhua
Gou, Fangfang
Wu, Jia
author_sort Lv, Baolong
collection PubMed
description Bone malignant tumors are metastatic and aggressive. The manual screening of medical images is time-consuming and laborious, and computer technology is now being introduced to aid in diagnosis. Due to a large amount of noise and blurred lesion edges in osteosarcoma MRI images, high-precision segmentation methods require large computational resources and are difficult to use in developing countries with limited conditions. Therefore, this study proposes an artificial intelligence-aided diagnosis scheme by enhancing image edge features. First, a threshold screening filter (TSF) was used to pre-screen the MRI images to filter redundant data. Then, a fast NLM algorithm was introduced for denoising. Finally, a segmentation method with edge enhancement (TBNet) was designed to segment the pre-processed images by fusing Transformer based on the UNet network. TBNet is based on skip-free connected U-Net and includes a channel-edge cross-fusion transformer and a segmentation method with a combined loss function. This solution optimizes diagnostic efficiency and solves the segmentation problem of blurred edges, providing more help and reference for doctors to diagnose osteosarcoma. The results based on more than 4000 osteosarcoma MRI images show that our proposed method has a good segmentation effect and performance, with Dice Similarity Coefficient (DSC) reaching 0.949, and show that other evaluation indexes such as Intersection of Union (IOU) and recall are better than other methods.
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spelling pubmed-100476402023-03-29 Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images Lv, Baolong Liu, Feng Li, Yulin Nie, Jianhua Gou, Fangfang Wu, Jia Diagnostics (Basel) Article Bone malignant tumors are metastatic and aggressive. The manual screening of medical images is time-consuming and laborious, and computer technology is now being introduced to aid in diagnosis. Due to a large amount of noise and blurred lesion edges in osteosarcoma MRI images, high-precision segmentation methods require large computational resources and are difficult to use in developing countries with limited conditions. Therefore, this study proposes an artificial intelligence-aided diagnosis scheme by enhancing image edge features. First, a threshold screening filter (TSF) was used to pre-screen the MRI images to filter redundant data. Then, a fast NLM algorithm was introduced for denoising. Finally, a segmentation method with edge enhancement (TBNet) was designed to segment the pre-processed images by fusing Transformer based on the UNet network. TBNet is based on skip-free connected U-Net and includes a channel-edge cross-fusion transformer and a segmentation method with a combined loss function. This solution optimizes diagnostic efficiency and solves the segmentation problem of blurred edges, providing more help and reference for doctors to diagnose osteosarcoma. The results based on more than 4000 osteosarcoma MRI images show that our proposed method has a good segmentation effect and performance, with Dice Similarity Coefficient (DSC) reaching 0.949, and show that other evaluation indexes such as Intersection of Union (IOU) and recall are better than other methods. MDPI 2023-03-10 /pmc/articles/PMC10047640/ /pubmed/36980371 http://dx.doi.org/10.3390/diagnostics13061063 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lv, Baolong
Liu, Feng
Li, Yulin
Nie, Jianhua
Gou, Fangfang
Wu, Jia
Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images
title Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images
title_full Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images
title_fullStr Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images
title_full_unstemmed Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images
title_short Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images
title_sort artificial intelligence-aided diagnosis solution by enhancing the edge features of medical images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047640/
https://www.ncbi.nlm.nih.gov/pubmed/36980371
http://dx.doi.org/10.3390/diagnostics13061063
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