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Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study

Determination of salivary flow rate and oral status in patients with primary Sjögren’s Syndrome (pSS) and diffuse cutaneous systemic sclerosis (dcSSc) and comparison with control subjects. Thirty-one pSS patients, 28 dcSSc patients, and 28 control subjects participated in this single-center, cross-s...

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Autores principales: Glavina, Ana, Božić, Ivona, Parat, Katica, Perković, Dijana, Biočina-Lukenda, Dolores, Martinović Kaliterna, Dušanka, Radić, Mislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047642/
https://www.ncbi.nlm.nih.gov/pubmed/36980365
http://dx.doi.org/10.3390/diagnostics13061057
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author Glavina, Ana
Božić, Ivona
Parat, Katica
Perković, Dijana
Biočina-Lukenda, Dolores
Martinović Kaliterna, Dušanka
Radić, Mislav
author_facet Glavina, Ana
Božić, Ivona
Parat, Katica
Perković, Dijana
Biočina-Lukenda, Dolores
Martinović Kaliterna, Dušanka
Radić, Mislav
author_sort Glavina, Ana
collection PubMed
description Determination of salivary flow rate and oral status in patients with primary Sjögren’s Syndrome (pSS) and diffuse cutaneous systemic sclerosis (dcSSc) and comparison with control subjects. Thirty-one pSS patients, 28 dcSSc patients, and 28 control subjects participated in this single-center, cross-sectional study. Unstimulated whole salivary flow rate (UWSFR) and stimulated whole salivary flow rate (SWSFR), salivary pH, DMFT index (D—decayed, M—missing, F—filled tooth), periodontal pocket depth (PPD), clinical attachment level (CAL), interincisal distance, and OHRQoL (oral health-related quality of life) were analyzed in all three groups of subjects. Primary SS and dcSSc patients had statistically significant lower values of UWSFR (0.20; 0.38 vs. 0.91 mL/min) and SWSFR (0.56; 0.70 vs. 1.64 mL/min) compared with control subjects (p < 0.001, Kruskal-Wallis test). Salivary pH values were statistically significantly lower in pSS and dcSSc patients compared with control subjects (6.00; 6.25 vs. 7.00, respectively) (p < 0.001, Kruskal-Wallis test). The DMFT index of dcSSc patients was higher (28.50) and statistically significant compared to control subjects (20.00) (p = 0.01). The prevalence of periodontitis was the same in pSS and dcSSc patients and control subjects (p = 0.384). Primary SS and dcSSc patients had a statistically significant decreased interincisal distance compared to control subjects (43.80; 38.00 vs. 48.00) (p = 0.003 and p < 0.001, respectively). Primary SS and dcSSc patients show decreased UWSFR and SWSFR, salivary pH values closer to an acidic medium, higher DMFT index, higher prevalence of periodontitis, decreased interincisal distance, and poorer OHRQoL, i.e., poor oral and periodontal health.
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spelling pubmed-100476422023-03-29 Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study Glavina, Ana Božić, Ivona Parat, Katica Perković, Dijana Biočina-Lukenda, Dolores Martinović Kaliterna, Dušanka Radić, Mislav Diagnostics (Basel) Article Determination of salivary flow rate and oral status in patients with primary Sjögren’s Syndrome (pSS) and diffuse cutaneous systemic sclerosis (dcSSc) and comparison with control subjects. Thirty-one pSS patients, 28 dcSSc patients, and 28 control subjects participated in this single-center, cross-sectional study. Unstimulated whole salivary flow rate (UWSFR) and stimulated whole salivary flow rate (SWSFR), salivary pH, DMFT index (D—decayed, M—missing, F—filled tooth), periodontal pocket depth (PPD), clinical attachment level (CAL), interincisal distance, and OHRQoL (oral health-related quality of life) were analyzed in all three groups of subjects. Primary SS and dcSSc patients had statistically significant lower values of UWSFR (0.20; 0.38 vs. 0.91 mL/min) and SWSFR (0.56; 0.70 vs. 1.64 mL/min) compared with control subjects (p < 0.001, Kruskal-Wallis test). Salivary pH values were statistically significantly lower in pSS and dcSSc patients compared with control subjects (6.00; 6.25 vs. 7.00, respectively) (p < 0.001, Kruskal-Wallis test). The DMFT index of dcSSc patients was higher (28.50) and statistically significant compared to control subjects (20.00) (p = 0.01). The prevalence of periodontitis was the same in pSS and dcSSc patients and control subjects (p = 0.384). Primary SS and dcSSc patients had a statistically significant decreased interincisal distance compared to control subjects (43.80; 38.00 vs. 48.00) (p = 0.003 and p < 0.001, respectively). Primary SS and dcSSc patients show decreased UWSFR and SWSFR, salivary pH values closer to an acidic medium, higher DMFT index, higher prevalence of periodontitis, decreased interincisal distance, and poorer OHRQoL, i.e., poor oral and periodontal health. MDPI 2023-03-10 /pmc/articles/PMC10047642/ /pubmed/36980365 http://dx.doi.org/10.3390/diagnostics13061057 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Glavina, Ana
Božić, Ivona
Parat, Katica
Perković, Dijana
Biočina-Lukenda, Dolores
Martinović Kaliterna, Dušanka
Radić, Mislav
Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study
title Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study
title_full Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study
title_fullStr Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study
title_full_unstemmed Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study
title_short Salivary Flow Rate and Oral Status in Patients with Primary Sjögren’s Syndrome and Diffuse Cutaneous Systemic Sclerosis: A Cross-Sectional Study
title_sort salivary flow rate and oral status in patients with primary sjögren’s syndrome and diffuse cutaneous systemic sclerosis: a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047642/
https://www.ncbi.nlm.nih.gov/pubmed/36980365
http://dx.doi.org/10.3390/diagnostics13061057
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